Ramona Belfiore
Overview
Explore the profile of Ramona Belfiore including associated specialties, affiliations and a list of published articles.
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7
Citations
530
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Recent Articles
1.
Belfiore R, Rodin A, Ferreira E, Velazquez R, Branca C, Caccamo A, et al.
Aging Cell
. 2018 Nov;
18(1):e12873.
PMID: 30488653
Accumulation of amyloid-β (Aβ) and fibrillary tangles, as well as neuroinflammation and memory loss, are hallmarks of Alzheimer's disease (AD). After almost 15 years from their generation, 3xTg-AD mice are...
2.
Velazquez R, Ferreira E, Tran A, Turner E, Belfiore R, Branca C, et al.
Aging Cell
. 2018 May;
17(4):e12775.
PMID: 29749079
Misfolded and hyperphosphorylated tau accumulates in several neurodegenerative disorders including Alzheimer's disease, frontotemporal dementia with Parkinsonism, corticobasal degeneration, progressive supranuclear palsy, Down syndrome, and Pick's disease. Tau is a microtubule-binding...
3.
Caccamo A, Belfiore R, Oddo S
Neurobiol Aging
. 2018 May;
68:1.
PMID: 29729422
Alzheimer's disease (AD) is the most common neurodegenerative disease. The causes of sporadic AD, which represents more than 95% of AD cases, are unknown. Several AD risk factors have been...
4.
Branca C, Shaw D, Belfiore R, Gokhale V, Shaw A, Foley C, et al.
Aging Cell
. 2017 Aug;
16(5):1146-1154.
PMID: 28779511
There is an urgent need for the development of new therapeutic strategies for Alzheimer's disease (AD). The dual-specificity tyrosine phosphorylation-regulated kinase-1A (Dyrk1a) is a protein kinase that phosphorylates the amyloid...
5.
Caccamo A, Branca C, Piras I, Ferreira E, Huentelman M, Liang W, et al.
Nat Neurosci
. 2017 Aug;
20(9):1236-1246.
PMID: 28758999
Alzheimer's disease (AD) is characterized by severe neuronal loss; however, the mechanisms by which neurons die remain elusive. Necroptosis, a programmed form of necrosis, is executed by the mixed lineage...
6.
Saletti R, Reina S, Pittala M, Belfiore R, Cunsolo V, Messina A, et al.
Biochim Biophys Acta Biomembr
. 2016 Dec;
1859(3):301-311.
PMID: 27989743
Voltage-dependent anion selective channels (VDACs) are integral membrane proteins found in the mitochondrial outer membrane. In comparison with the most abundant isoform VDAC1, there is little knowledge about the functional...
7.
Magri A, Belfiore R, Reina S, Tomasello M, Di Rosa M, Guarino F, et al.
Sci Rep
. 2016 Oct;
6:34802.
PMID: 27721436
Superoxide Dismutase 1 mutants associate with 20-25% of familial Amyotrophic Lateral Sclerosis (ALS) cases, producing toxic aggregates on mitochondria, notably in spinal cord. The Voltage Dependent Anion Channel isoform 1...