Ramesh Ekambaram
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Explore the profile of Ramesh Ekambaram including associated specialties, affiliations and a list of published articles.
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8
Citations
15
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Recent Articles
1.
Honkanen M, Narvi E, Ojala V, Jokilammi A, Rantakari P, Kronqvist P, et al.
Chembiochem
. 2024 Jun;
25(18):e202400264.
PMID: 38864514
Triacedimannose (TADM) is a synthetic trivalent acetylated glycocluster and a transmembrane macrophage activator independent of the mannose receptor. TADM induces Th1-type immune responses and suppresses Th2-type cytokines in acute and...
2.
Eichin D, Rahkila J, Li X, Ekambaram R, Lassfolk R, Leino R, et al.
Carbohydr Res
. 2024 May;
541:109166.
PMID: 38815341
Triacedimannose (TADM) is a synthetic trivalent acetylated glycocluster comprising β-1,2-linked mannobioses that in humans induces TNF in vitro and in vivo. The purpose of this study was to analyze whether...
3.
Nonga O, Lavogina D, Enkvist E, Kestav K, Chaikuad A, Dixon-Clarke S, et al.
Molecules
. 2021 Jul;
26(14).
PMID: 34299628
We performed an X-ray crystallographic study of complexes of protein kinase PIM-1 with three inhibitors comprising an adenosine mimetic moiety, a linker, and a peptide-mimetic (d-Arg) fragment. Guided by the...
4.
Pietsch M, Viht K, Schnitzler A, Ekambaram R, Steinkruger M, Enkvist E, et al.
Bioorg Chem
. 2020 Feb;
96:103608.
PMID: 32058103
Protein kinase CK2, a heterotetrameric holoenzyme composed of two catalytic chains (CK2α) attached to a homodimer of regulatory subunits (CK2β), is a target for drug development for cancer therapy. Here,...
5.
Ekambaram R, Enkvist E, Manoharan G, Ugandi M, Kasari M, Viht K, et al.
Chem Commun (Camb)
. 2014 Mar;
50(31):4096-8.
PMID: 24619026
Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to...
6.
Ekambaram R, Enkvist E, Vaasa A, Kasari M, Raidaru G, Knapp S, et al.
ChemMedChem
. 2013 Apr;
8(6):909-13.
PMID: 23616352
Potent and selective: The unique nature of the ATP binding pocket structure of Pim family protein kinases (PKs) was used for the development of bisubstrate inhibitors and a fluorescent probe...
7.
Sainath Rao S, Raghunathan R, Ekambaram R, Raghunathan M
Antimicrob Agents Chemother
. 2009 Sep;
53(12):5317-8.
PMID: 19738013
No abstract available.
8.
Sainath Rao S, Raghunathan R, Ekambaram R, Raghunathan M
Int J Antimicrob Agents
. 2009 Jul;
34(5):451-3.
PMID: 19625168
Two hundred isolates of Mycobacterium tuberculosis were evaluated for their susceptibility to a newly synthesised quinolone derivative, ER-2, compared with ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin. ER-2 and moxifloxacin showed the...