Ramakumar Tummala
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Explore the profile of Ramakumar Tummala including associated specialties, affiliations and a list of published articles.
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31
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734
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Recent Articles
1.
Mandal J, Aryal S, Manandhar I, Chakraborty S, Mei X, Yeoh B, et al.
bioRxiv
. 2025 Jan;
PMID: 39763881
Starvation, intermittent fasting and exercise, all of which are recommended lifestyle modifiers share a common metabolic signature, ketogenesis to generate the ketone bodies, predominantly β-hydroxybutyrate. β-hydroxybutyrate exerts beneficial effects across...
2.
Bardhan P, Mei X, Lai N, Mell B, Tummala R, Aryal S, et al.
Circ Res
. 2024 Oct;
135(12):1122-1137.
PMID: 39440438
Background: Tryptophan metabolism is important in blood pressure regulation. The tryptophan-indole pathway is exclusively mediated by the gut microbiota. ACE2 (angiotensin-converting enzyme 2) participates in tryptophan absorption, and a lack...
3.
Aryal S, Manandhar I, Mei X, Yeoh B, Tummala R, Saha P, et al.
Camb Prism Precis Med
. 2024 Mar;
1:e26.
PMID: 38550938
The single largest contributor to human mortality is cardiovascular disease, the top risk factor for which is hypertension (HTN). The last two decades have placed much emphasis on the identification...
4.
Sakamuri A, Bardhan P, Tummala R, Mauvais-Jarvis F, Yang T, Joe B, et al.
Microbiota Host
. 2023 Nov;
1(1).
PMID: 37937163
Microbiota composition is known to be linked to sex. However, separating sex hormones and sex chromosome roles in gut microbial diversity is yet to be determined. To investigate the sex...
5.
Mei X, Mell B, Aryal S, Manandhar I, Tummala R, Zubcevic J, et al.
Pharmacol Res
. 2023 Sep;
196:106920.
PMID: 37716548
Engineered gut microbiota represents a new frontier in medicine, in part serving as a vehicle for the delivery of therapeutic biologics to treat a range of host conditions. The gut...
6.
Gudneppanavar R, Sabu Kattuman E, Teegala L, Southard E, Tummala R, Joe B, et al.
J Cell Mol Med
. 2023 Aug;
27(19):2983-2994.
PMID: 37603611
Short-chain fatty acid butyrate is produced from the bacterial fermentation of indigestible fiber in the intestinal lumen, and it has been shown to attenuate lung inflammation in murine asthma models....
7.
Golonka R, Yeoh B, Saha P, Gohara A, Tummala R, Stepkowski S, et al.
Hepatol Commun
. 2023 May;
7(6).
PMID: 37219858
Background: HCC is the most common primary liver cancer and a leading cause of cancer-related mortality. Gut microbiota is a large collection of microbes, predominately bacteria, that harbor the gastrointestinal...
8.
Du Toit C, Tran T, Deo N, Aryal S, Lip S, Sykes R, et al.
J Am Heart Assoc
. 2023 Apr;
12(9):e027896.
PMID: 37119074
Background Machine learning (ML) is pervasive in all fields of research, from automating tasks to complex decision-making. However, applications in different specialities are variable and generally limited. Like other conditions,...
9.
Li J, Richards E, Tummala R, Pepine C, Raizada M, Yang T
J Am Heart Assoc
. 2023 Feb;
12(4):e027918.
PMID: 36752270
Background Hypertension is associated with gut dysbiosis, altered intestinal immunity, and gut pathology in animal models and humans. Although these findings have implicated impaired interactions between gut and gut microbiota...
10.
Mei X, Mell B, Manandhar I, Aryal S, Tummala R, Kyoung J, et al.
J Am Heart Assoc
. 2022 Dec;
11(24):e027893.
PMID: 36533597
Background The gut and gut microbiota, which were previously neglected in blood pressure regulation, are becoming increasingly recognized as factors contributing to hypertension. Diseases affecting the gut such as inflammatory...