Ramakrishna Hegde
Overview
Explore the profile of Ramakrishna Hegde including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
235
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Recent Articles
1.
Sindberg G, Callen S, Banerjee S, Meng J, Hale V, Hegde R, et al.
J Neuroimmune Pharmacol
. 2018 Sep;
14(2):200-214.
PMID: 30242614
Human Immunodeficiency Virus (HIV) pathogenesis has been closely linked with microbial translocation, which is believed to drive inflammation and HIV replication. Opioid drugs have been shown to worsen this symptom,...
2.
Gundavarapu S, Mishra N, Singh S, Langley R, Saeed A, Feghali-Bostwick C, et al.
PLoS One
. 2013 Oct;
8(10):e77160.
PMID: 24155926
Lung diseases such as chronic obstructive pulmonary disease (COPD), asthma, and lung infections are major causes of morbidity and mortality among HIV-infected patients even in the era of antiretroviral therapy...
3.
Arrode-Bruses G, Hegde R, Jin Y, Liu Z, Narayan O, Chebloune Y
Vaccine
. 2012 Mar;
30(19):2956-62.
PMID: 22387218
Increasing the safety and the efficacy of existing HIV vaccines is one of the strategies that could help to promote the development of a vaccine for human use. We developed...
4.
Bokhari S, Hegde R, Callen S, Yao H, Adany I, Li Q, et al.
J Neuroimmune Pharmacol
. 2011 Mar;
6(4):626-39.
PMID: 21431470
Despite the advent of antiretroviral therapy, complications of HIV-1 infection with concurrent drug abuse are an emerging problem. Opiates are well known to modulate immune responses by preventing the development...
5.
Arrode-Bruses G, Sheffer D, Hegde R, Dhillon S, Liu Z, Villinger F, et al.
J Virol
. 2009 Nov;
84(3):1243-53.
PMID: 19923181
The optimization of immune responses (IR) induced by HIV DNA vaccines in humans is one of the great challenges in the development of an effective vaccine against AIDS. Ideally, this...
6.
Bokhari S, Yao H, Bethel-Brown C, Fuwang P, Williams R, Dhillon N, et al.
J Neurovirol
. 2009 May;
15(3):219-28.
PMID: 19462331
There is increasing evidence that opiates accelerate the pathogenesis and progression of acquired immunodeficiency syndrome (AIDS), as well as the incidence of human immunodeficiency virus (HIV) encephalitis (HIVE), a condition...
7.
Arrode G, Hegde R, Jin Y, Singh D, Narayan O, Chebloune Y
Vaccine
. 2008 Jul;
26(31):3795-804.
PMID: 18586360
Gag-CD8+ T cell responses are associated with immune control of HIV infection. Since during HIV infection Nef impairs T cell responses, we evaluated whether deletion of nef from a non-infectious...
8.
Arrode G, Hegde R, Mani A, Jin Y, Chebloune Y, Narayan O
J Immunol
. 2007 Feb;
178(4):2318-27.
PMID: 17277137
HIV DNA vaccines are potent inducers of cell-mediated immune (CMI) response in mice but elicit poor HIV-specific IFN-gamma-producing T cells in monkeys and humans. In this study, we performed kinetic...
9.
Kan-Mitchell J, Bajcz M, Schaubert K, Price D, Brenchley J, Asher T, et al.
J Immunol
. 2006 May;
176(11):6690-701.
PMID: 16709828
CD8+ CTL responses are important for the control of HIV-1 infection. The immunodominant HLA-A2-restricted Gag epitope, SLYNTVATL (SL9), is considered to be a poor immunogen because reactivity to it is...
10.
Liu Z, Singh D, Sheffer D, Smith M, Dhillon S, Chebloune Y, et al.
Virology
. 2006 May;
351(2):444-54.
PMID: 16650448
We earlier reported that immunization of macaques with a reverse transcriptase-deleted SHIV(KU2) (DeltartSHIV(KU2)) plasmid that contained HIV-1(HXB2) env and SIV gag-nef induced protection against AIDS caused by challenge virus SHIV89.6P...