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Ram B Khattri

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Articles 20
Citations 199
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Recent Articles
1.
Khattri R, Batra A, White Z, Hammers D, Ryan T, Barton E, et al.
Skelet Muscle . 2024 Dec; 14(1):36. PMID: 39716324
Despite its notoriously mild phenotype, the dystrophin-deficient mdx mouse is the most common model of Duchenne muscular dystrophy (DMD). By mimicking a human DMD-associated metabolic comorbidity, hyperlipidemia, in mdx mice...
2.
Khattri R, Louis L, Kim K, Anderson E, Fazzone B, Harland K, et al.
Sci Rep . 2023 Oct; 13(1):16811. PMID: 37798334
For end-stage kidney disease (ESKD) patients, hemodialysis requires durable vascular access which is often surgically created using an arteriovenous fistula (AVF). However, some ESKD patients that undergo AVF placement develop...
3.
Frost C, Ramirez-Mata A, Khattri R, Merritt M, Frost S
PLoS One . 2023 Mar; 18(3):e0281396. PMID: 36893152
Hypoxia is a common feature of most solid tumors, one that favors tumor progression and limits treatment effectiveness. Targeting hypoxia has long been a goal in cancer therapy, by identifying...
4.
Khattri R, Puglise J, Ryan T, Walter G, Merritt M, Barton E
Metabolomics . 2022 Dec; 18(12):105. PMID: 36480060
Introduction: Fuel sources for skeletal muscle tissue include carbohydrates and fatty acids, and utilization depends upon fiber type, workload, and substrate availability. The use of isotopically labeled substrate tracers combined...
5.
Khattri R, Batra A, Matheny M, Hart C, Henley-Beasley S, Hammers D, et al.
NMR Biomed . 2022 Nov; 36(3):e4869. PMID: 36331178
Rodent models of Duchenne muscular dystrophy (DMD) often do not recapitulate the severity of muscle wasting and resultant fibro-fatty infiltration observed in DMD patients. Having recently documented severe muscle wasting...
6.
Palzkill V, Thome T, Murillo A, Khattri R, Ryan T
Front Physiol . 2022 Oct; 13:992413. PMID: 36246103
L-Kynurenine (L-Kyn), a product of tryptophan (Trp) catabolism, has been linked with impairments in walking speed, muscle strength/size, and physical function. The purpose of this pilot study was to develop...
7.
Khattri R, Kim K, Anderson E, Fazzone B, Harland K, Hu Q, et al.
Am J Physiol Renal Physiol . 2022 Aug; 323(5):F577-F589. PMID: 36007889
End-stage kidney disease, the most advanced stage of chronic kidney disease (CKD), requires renal replacement therapy or kidney transplant to sustain life. To accomplish durable dialysis access, the creation of...
8.
Khattri R, Thome T, Fitzgerald L, Wohlgemuth S, Hepple R, Ryan T
Toxics . 2022 Mar; 10(3). PMID: 35324765
Tobacco smoke-related diseases such as chronic obstructive pulmonary disease (COPD) are associated with high healthcare burden and mortality rates. Many COPD patients were reported to have muscle atrophy and weakness,...
9.
Henry J, Khattri R, Guingab-Cagmat J, Merritt M, Garrett T, Patterson J, et al.
Metabolomics . 2021 Jun; 17(7):60. PMID: 34143280
Introduction: Research aimed at understanding intraspecific variation among corals could substantially increase understanding of coral biology and improve outcomes of active restoration efforts. Metabolomics is useful for identifying physiological drivers...
10.
Khattri R, Kim K, Thome T, Salyers Z, OMalley K, Berceli S, et al.
J Clin Med . 2021 Feb; 10(3). PMID: 33540726
Chronic limb threatening ischemia (CLTI) is the most severe manifestation of peripheral atherosclerosis. Patients with CLTI have poor muscle quality and function and are at high risk for limb amputation...