Ralph Schlapbach
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Explore the profile of Ralph Schlapbach including associated specialties, affiliations and a list of published articles.
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93
Citations
2775
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Recent Articles
1.
Wolski W, Grossmann J, Schwarz L, Leary P, Turker C, Nanni P, et al.
J Proteome Res
. 2025 Jan;
24(2):955-965.
PMID: 39849819
Mass spectrometry is a cornerstone of quantitative proteomics, enabling relative protein quantification and differential expression analysis () of proteins. As experiments grow in complexity, involving more samples, groups, and identified...
2.
Hausmann F, Caldi Gomes L, Hanzelmann S, Khatri R, Oller S, Gebelin M, et al.
Gigascience
. 2024 Dec;
13.
PMID: 39693632
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease, which still lacks effective disease-modifying therapies. Similar to other neurodegenerative disorders, such as Alzheimer and Parkinson disease, ALS pathology...
3.
Walchli T, Ghobrial M, Schwab M, Takada S, Zhong H, Suntharalingham S, et al.
Nature
. 2024 Jul;
632(8025):603-613.
PMID: 38987604
A broad range of brain pathologies critically relies on the vasculature, and cerebrovascular disease is a leading cause of death worldwide. However, the cellular and molecular architecture of the human...
4.
Beltrao P, Van Den Bossche T, Gabriels R, Holstein T, Kockmann T, Nameni A, et al.
J Proteomics
. 2024 Jul;
305:105246.
PMID: 38964537
The 2023 European Bioinformatics Community for Mass Spectrometry (EuBIC-MS) Developers Meeting was held from January 15th to January 20th, 2023, in Congressi Stefano Franscin at Monte Verità in Ticino, Switzerland....
5.
Caldi Gomes L, Hanzelmann S, Hausmann F, Khatri R, Oller S, Parvaz M, et al.
Nat Commun
. 2024 Jun;
15(1):4893.
PMID: 38849340
Amyotrophic lateral sclerosis (ALS) is a debilitating motor neuron disease and lacks effective disease-modifying treatments. This study utilizes a comprehensive multiomic approach to investigate the early and sex-specific molecular mechanisms...
6.
Lin C, Canonica F, Wuthrich S, Fettelschoss-Gabriel A, Schlapbach R, Nanni P
J Chromatogr A
. 2024 Apr;
1722:464828.
PMID: 38581973
The linkages of disulfide bond (DSB) play important roles in protein stability and activity. Mass spectrometry-based (MS-based) techniques become accepted tools for DSB analysis in the recent decade. In the...
7.
Ryan F, Francos-Quijorna I, Hernandez-Mir G, Aquino C, Schlapbach R, Bradbury E, et al.
J Neurosci
. 2024 Feb;
44(6).
PMID: 38326029
Toll-like receptors (TLRs) play an important role in the innate immune response after CNS injury. Although TLR4 is one of the best characterized, its role in chronic stages after spinal...
8.
Nanni P, Gehrig P, Schlapbach R
Chimia (Aarau)
. 2023 Dec;
76(1-2):73-80.
PMID: 38069752
Mass spectrometry is a powerful tool in the hand of life science researchers, who constantly develop and apply new methods for the investigation of biomolecules, such as proteins, peptides, metabolites,...
9.
Chatterjee M, Roschitzki B, Grossmann J, Rathinam M, Kunz L, Wolski W, et al.
Int J Biol Macromol
. 2023 Oct;
254(Pt 1):127666.
PMID: 37890743
The spotted pod borer, Maruca vitrata (Lepidoptera: Crambidae) is a destructive insect pest that inflicts significant productivity losses on important leguminous crops. Unravelling insect proteomes is vital to comprehend their...
10.
Wolski W, Nanni P, Grossmann J, dErrico M, Schlapbach R, Panse C
J Proteome Res
. 2023 Mar;
22(4):1092-1104.
PMID: 36939687
Mass spectrometry is widely used for quantitative proteomics studies, relative protein quantification, and differential expression analysis of proteins. There is a large variety of quantification software and analysis tools. Nevertheless,...