Ralph S Marcucio
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Explore the profile of Ralph S Marcucio including associated specialties, affiliations and a list of published articles.
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82
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2715
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Recent Articles
11.
Green R, Lo Vercio L, Dauter A, Barretto E, Devine J, Vidal-Garcia M, et al.
bioRxiv
. 2023 May;
PMID: 37214859
Morphogenesis requires highly coordinated, complex interactions between cellular processes: proliferation, migration, and apoptosis, along with physical tissue interactions. How these cellular and tissue dynamics drive morphogenesis remains elusive. Three dimensional...
12.
Lo Vercio L, Green R, Robertson S, Guo S, Dauter A, Marchini M, et al.
IEEE Access
. 2023 Jan;
10:105084-105100.
PMID: 36660260
A variety of genetic mutations affect cell proliferation during organism development, leading to structural birth defects. However, the mechanisms by which these alterations influence the development of the face remain...
13.
Zbasnik N, Dolan K, Buczkowski S, Green R, Hallgrimsson B, Marcucio R, et al.
Dev Dyn
. 2022 May;
251(10):1711-1727.
PMID: 35618654
Background: Asymmetries in craniofacial anomalies are commonly observed. In the facial skeleton, the left side is more commonly and/or severely affected than the right. Such asymmetries complicate treatment options. Mechanisms...
14.
Devine J, Vidal-Garcia M, Liu W, Neves A, Lo Vercio L, Green R, et al.
Sci Data
. 2022 May;
9(1):230.
PMID: 35614082
Complex morphological traits are the product of many genes with transient or lasting developmental effects that interact in anatomical context. Mouse models are a key resource for disentangling such effects,...
15.
Aponte J, Katz D, Roth D, Vidal-Garcia M, Liu W, Andrade F, et al.
Elife
. 2021 Nov;
10.
PMID: 34779766
Realistic mappings of genes to morphology are inherently multivariate on both sides of the equation. The importance of coordinated gene effects on morphological phenotypes is clear from the intertwining of...
16.
Lackner I, Weber B, Haffner-Luntzer M, Hristova S, Gebhard F, Lam C, et al.
J Orthop Translat
. 2021 Mar;
28:39-46.
PMID: 33717980
Background: Trauma is the leading cause of death and disability worldwide, especially in the young population. Cardiac injuries are an independent predictor for a poor overall outcome after trauma. The...
17.
Hu D, Marcucio R
J Vis Exp
. 2021 Mar;
(168).
PMID: 33682859
The avian embryo has been used as a model system for more than a century and has led to fundamental understanding of vertebrate development. One of the strengths of this...
18.
Rivera K, Russo F, Boileau R, Tomlinson R, Miclau T, Marcucio R, et al.
Sci Rep
. 2020 Dec;
10(1):22241.
PMID: 33335129
There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture...
19.
Wong S, Hu D, Slocum J, Lam C, Nguyen M, Miclau T, et al.
J Orthop Res
. 2020 Nov;
39(8):1622-1632.
PMID: 33140859
The majority of fracture research has been conducted using long bone fracture models, with significantly less research into the mechanisms driving craniofacial repair. However, craniofacial bones differ from long bones...
20.
Katz D, Aponte J, Liu W, Green R, Mayeux J, Pollard K, et al.
PLoS One
. 2020 Jun;
15(6):e0233377.
PMID: 32502155
The biology of how faces are built and come to differ from one another is complex. Discovering normal variants that contribute to differences in facial morphology is one key to...