Ralph Riedl
Overview
Explore the profile of Ralph Riedl including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
728
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, et al.
Nat Commun
. 2020 Aug;
11(1):3913.
PMID: 32737318
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, et al.
Nat Commun
. 2020 Jul;
11(1):3387.
PMID: 32636417
Biosynthesis of glycosylphosphatidylinositol (GPI) is required for anchoring proteins to the plasma membrane, and is essential for the integrity of the fungal cell wall. Here, we use a reporter gene-based...
3.
Pries V, Nocker C, Khan D, Johnen P, Hong Z, Tripathi A, et al.
Cell Chem Biol
. 2018 Jan;
25(3):279-290.e7.
PMID: 29307839
Invasive fungal infections are accompanied by high mortality rates that range up to 90%. At present, only three different compound classes are available for use in the clinic, and these...
4.
Elling U, Wimmer R, Leibbrandt A, Burkard T, Michlits G, Leopoldi A, et al.
Nature
. 2017 Sep;
550(7674):114-118.
PMID: 28953874
The ability to directly uncover the contributions of genes to a given phenotype is fundamental for biology research. However, ostensibly homogeneous cell populations exhibit large clonal variance that can confound...
5.
Estoppey D, Lee C, Janoschke M, Lee B, Wan K, Dong H, et al.
Cell Rep
. 2017 Apr;
19(3):451-460.
PMID: 28423309
Flavivirus infections by Zika and dengue virus impose a significant global healthcare threat with no US Food and Drug Administration (FDA)-approved vaccination or specific antiviral treatment available. Here, we present...
6.
Filipuzzi I, Cotesta S, Perruccio F, Knapp B, Fu Y, Studer C, et al.
PLoS Genet
. 2016 Nov;
12(11):e1006374.
PMID: 27855158
Invasive infections by fungal pathogens cause more deaths than malaria worldwide. We found the ergoline compound NGx04 in an antifungal screen, with selectivity over mammalian cells. High-resolution chemogenomics identified the...
7.
Pries V, Cotesta S, Riedl R, Aust T, Schuierer S, Tao J, et al.
J Biomol Screen
. 2015 Oct;
21(3):306-15.
PMID: 26459507
Phenotypic screens are effective starting points to identify compounds with desirable activities. To find novel antifungals, we conducted a phenotypic screen in Saccharomyces cerevisiae and identified two discrete scaffolds with...
8.
Helliwell S, Karkare S, Bergdoll M, Rahier A, Leighton-Davis J, Fioretto C, et al.
Nat Commun
. 2015 Oct;
6:8613.
PMID: 26456460
FR171456 is a natural product with cholesterol-lowering properties in animal models, but its molecular target is unknown, which hinders further drug development. Here we show that FR171456 specifically targets the...
9.
Krastel P, Roggo S, Schirle M, Ross N, Perruccio F, Aspesi Jr P, et al.
Angew Chem Int Ed Engl
. 2015 Jul;
54(35):10149-54.
PMID: 26179970
Cultivation of myxobacteria of the Nannocystis genus led to the isolation and structure elucidation of a class of novel cyclic lactone inhibitors of elongation factor 1. Whole genome sequence analysis...
10.
Junne T, Wong J, Studer C, Aust T, Bauer B, Beibel M, et al.
J Cell Sci
. 2015 Jan;
128(6):1217-29.
PMID: 25616894
A new cyclic decadepsipeptide was isolated from Chaetosphaeria tulasneorum with potent bioactivity on mammalian and yeast cells. Chemogenomic profiling in S. cerevisiae indicated that the Sec61 translocon complex, the machinery...