Ralph Buttyan
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Explore the profile of Ralph Buttyan including associated specialties, affiliations and a list of published articles.
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66
Citations
1384
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Recent Articles
1.
Yenki P, Bhasin S, Liu L, Nabavi N, Cheng C, Tam K, et al.
Endocr Relat Cancer
. 2023 Oct;
30(12).
PMID: 37800655
Intratumoral androgen biosynthesis contributes to castration-resistant prostate cancer progression in patients treated with androgen deprivation therapy. The molecular mechanisms by which castration-resistant prostate cancer acquires the capacity for androgen biosynthesis...
2.
Singh N, Ramnarine V, Song J, Pandey R, Padi S, Nouri M, et al.
Nat Commun
. 2021 Dec;
12(1):7349.
PMID: 34934057
Neuroendocrine (NE) prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer (PCa) arising either de novo or from transdifferentiated prostate adenocarcinoma following androgen deprivation therapy (ADT). Extensive computational...
3.
Massah S, Foo J, Li N, Truong S, Nouri M, Xie L, et al.
Mol Cell Endocrinol
. 2020 Dec;
522:111136.
PMID: 33347954
Background: Gli is an oncogenic transcription factor family thought to be involved in breast cancer (BrCa) cell growth. Gli activity is regulated by a post-translational proteolytic process that is suppressed...
4.
Park E, Cox M, Scotland K, Buttyan R, Lange D
Cell Stress Chaperones
. 2020 Jan;
25(2):245-251.
PMID: 31970695
The purpose of the work was to investigate mechanisms of erythropoietin-induced protection and accelerated recovery of kidneys and ureters from obstructive injury. Unilateral ureteral obstruction was established for 24, 48,...
5.
Nouri M, Massah S, Caradec J, Lubik A, Li N, Truong S, et al.
Clin Cancer Res
. 2020 Jan;
26(7):1678-1689.
PMID: 31919137
Purpose: Patients with metastatic prostate cancer are increasingly presenting with treatment-resistant, androgen receptor-negative/low (AR) tumors, with or without neuroendocrine characteristics, in processes attributed to tumor cell plasticity. This plasticity has...
6.
Ramnarine V, Kobelev M, Gibb E, Nouri M, Lin D, Wang Y, et al.
Eur Urol
. 2019 Aug;
76(5):546-559.
PMID: 31445843
Context: It is increasingly evident that non-protein-coding regions of the genome can give rise to transcripts that form functional layers of the cancer genome. One of most abundant classes in...
7.
Raven P, Lysakowski S, Tan Z, DCosta N, Moskalev I, Frees S, et al.
J Cell Physiol
. 2019 Apr;
234(11):20634-20647.
PMID: 31012113
The sonic hedgehog (SHH) signaling pathway plays an integral role in the maintenance and progression of bladder cancer (BCa) and SHH inhibition may be an efficacious strategy for BCa treatment....
8.
Stylianou N, Lehman M, Wang C, Fard A, Rockstroh A, Fazli L, et al.
Oncogene
. 2018 Dec;
38(13):2436.
PMID: 30510231
Following the publication of the above article, the authors noted an error in Figure 4, panel B. The colours of the localized and mCRPC samples were accidentally switched. The authors...
9.
Stylianou N, Lehman M, Wang C, Fard A, Rockstroh A, Fazli L, et al.
Oncogene
. 2018 Sep;
38(7):913-934.
PMID: 30194451
The propensity of cancer cells to transition between epithelial and mesenchymal phenotypic states via the epithelial-mesenchymal transition (EMT) program can regulate metastatic processes, cancer progression, and treatment resistance. Transcriptional investigations...
10.
Chen R, Li Y, Buttyan R, Dong X
Oncotarget
. 2018 Jul;
9(51):29842.
PMID: 30038724
[This corrects the article DOI: 10.18632/oncotarget.19386.].