Ralph A DeFronzo
Overview
Explore the profile of Ralph A DeFronzo including associated specialties, affiliations and a list of published articles.
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Articles
332
Citations
20514
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Recent Articles
1.
Utzschneider K, Tripputi M, Butera N, Mari A, Rosin S, Banerji M, et al.
Diabetes Care
. 2025 Feb;
PMID: 39998948
Objective: To evaluate how model-based parameters of β-cell function change with glucose-lowering treatment and associate with glycemic deterioration in adults with type 2 diabetes (T2D). Research Design And Methods: In...
2.
Neppala S, Chigurupati H, Fath A, Jagirdhar G, Sandhyavenu H, Bolte J, et al.
Cardiovasc Revasc Med
. 2025 Jan;
PMID: 39765439
Background: Pulmonary hypertension (pHTN) has been associated with increased morbidity and mortality after mitral Transcatheter Edge-to-Edge Repair (TEER), but the association remains uncertain. This study aims to evaluate the impact...
3.
Cersosimo E, YueJuan Q, Baskoy G, Chavez A, Barkhordarian M, Hansis-Diarte A, et al.
Diabetes Obes Metab
. 2024 Nov;
27(2):944-952.
PMID: 39604709
Aims: To investigate the effect of sodium-glucose co-transporter 2 inhibitor [SGLT-2i] therapy on renal haemodynamics in T2D patients with glomerular hyperfiltration. Materials And Methods: Sixty T2D patients with elevated [HYPER]...
4.
Solis-Herrera C, Qin Y, Honka H, Cersosimo E, Triplitt C, Neppala S, et al.
Diabetes
. 2024 Oct;
74(1):43-52.
PMID: 39446133
Article Highlights:
5.
Merovci A, Finley B, Hansis-Diarte A, Neppala S, Abdul-Ghani M, Cersosimo E, et al.
BMJ Open Diabetes Res Care
. 2024 Oct;
12(5).
PMID: 39424350
Introduction: Low carbohydrate ketogenic diets have received renewed interest for the treatment of obesity and type 2 diabetes. These diets promote weight loss, improve glycemic control, and reduce insulin resistance....
6.
Schwartz S, Corkey B, Gavin 3rd J, DeFronzo R, Herman M
BMC Med
. 2024 Sep;
22(1):356.
PMID: 39227924
This review seeks to address major gaps and delays between our rapidly evolving body of knowledge on type 2 diabetes and its translation into real-world practice. Through updated and improved...
7.
Armato J, DeFronzo R, Abdul-Ghani M, Ruby R
J Clin Endocrinol Metab
. 2024 Aug;
PMID: 39109850
Background/aim: To examine if insulin resistance is associated with markers of glycemic, cardiometabolic and atherosclerotic risk in non-obese, non-prediabetic individuals compared to insulin sensitive subjects matched for BMI, gender, and...
8.
DeFronzo R, Auchus R, Bancos I, Blonde L, Busch R, Buse J, et al.
BMJ Open
. 2024 Jul;
14(7):e081121.
PMID: 39013654
Introduction: Even with recent treatment advances, type 2 diabetes (T2D) remains poorly controlled for many patients, despite the best efforts to adhere to therapies and lifestyle modifications. Although estimates vary,...
9.
Handelsman Y, Anderson J, Bakris G, Ballantyne C, Bhatt D, Bloomgarden Z, et al.
Metabolism
. 2024 Jun;
159:155931.
PMID: 38852020
The spectrum of cardiorenal and metabolic diseases comprises many disorders, including obesity, type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), dyslipidemias, hypertension, and...
10.
Neppala S, Rajan J, Yang E, DeFronzo R
Curr Cardiol Rep
. 2024 Apr;
26(6):623-633.
PMID: 38634964
Purpose Of Review: What is new? Cardiovascular disease (CVD) is the leading cause of mortality in type 2 diabetes (T2D) individuals. Of the major risk factors for CVD, less than...