Rajni Nigam
Overview
Explore the profile of Rajni Nigam including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
719
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Recent Articles
1.
Shimoyama M, Laulederkind S, De Pons J, Nigam R, Smith J, Tutaj M, et al.
Dis Model Mech
. 2016 Oct;
9(10):1089-1095.
PMID: 27736745
Rattus norvegicus, the laboratory rat, has been a crucial model for studies of the environmental and genetic factors associated with human diseases for over 150 years. It is the primary...
2.
Petri V, Hayman G, Tutaj M, Smith J, Laulederkind S, Wang S, et al.
Comput Struct Biotechnol J
. 2016 Sep;
14:35-48.
PMID: 27602200
Understanding the pathogenesis of disease is instrumental in delineating its progression mechanisms and for envisioning ways to counteract it. In the process, animal models represent invaluable tools for identifying disease-related...
3.
Wang S, Laulederkind S, Hayman G, Petri V, Smith J, Tutaj M, et al.
Physiol Genomics
. 2016 Jun;
48(8):589-600.
PMID: 27287925
Cardiovascular diseases are complex diseases caused by a combination of genetic and environmental factors. To facilitate progress in complex disease research, the Rat Genome Database (RGD) provides the community with...
4.
The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database
Hayman G, Laulederkind S, Smith J, Wang S, Petri V, Nigam R, et al.
Database (Oxford)
. 2016 Mar;
2016.
PMID: 27009807
The Rat Genome Database (RGD;http://rgd.mcw.edu/) provides critical datasets and software tools to a diverse community of rat and non-rat researchers worldwide. To meet the needs of the many users whose...
5.
Wang S, Laulederkind S, Hayman G, Petri V, Liu W, Smith J, et al.
Database (Oxford)
. 2015 Jan;
2015.
PMID: 25632109
Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been selectively bred for certain biological traits related...
6.
Liu W, Laulederkind S, Hayman G, Wang S, Nigam R, Smith J, et al.
Database (Oxford)
. 2015 Jan;
2015.
PMID: 25619558
The Rat Genome Database (RGD) is the premier repository of rat genomic, genetic and physiologic data. Converting data from free text in the scientific literature to a structured format is...
7.
Shimoyama M, De Pons J, Hayman G, Laulederkind S, Liu W, Nigam R, et al.
Nucleic Acids Res
. 2014 Oct;
43(Database issue):D743-50.
PMID: 25355511
The Rat Genome Database (RGD, http://rgd.mcw.edu) provides the most comprehensive data repository and informatics platform related to the laboratory rat, one of the most important model organisms for disease studies....
8.
Petri V, Hayman G, Tutaj M, Smith J, Laulederkind S, Wang S, et al.
Hum Genomics
. 2014 Oct;
8:17.
PMID: 25265995
Background: Biological systems are exquisitely poised to respond and adjust to challenges, including damage. However, sustained damage can overcome the ability of the system to adjust and result in a...
9.
Petri V, Jayaraman P, Tutaj M, Hayman G, Smith J, De Pons J, et al.
J Biomed Semantics
. 2014 Feb;
5(1):7.
PMID: 24499703
Background: The Pathway Ontology (PW) developed at the Rat Genome Database (RGD), covers all types of biological pathways, including altered and disease pathways and captures the relationships between them within...
10.
Nigam R, Munzenmaier D, Worthey E, Dwinell M, Shimoyama M, Jacob H
J Biomed Semantics
. 2013 Nov;
4(1):36.
PMID: 24267899
Background: The Rat Genome Database (RGD) ( http://rgd.mcw.edu/) is the premier site for comprehensive data on the different strains of the laboratory rat (Rattus norvegicus). The strain data are collected...