Rajeshwary Ghosh
Overview
Explore the profile of Rajeshwary Ghosh including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
428
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ghosh R, Pattison J
Autophagy Rep
. 2024 Oct;
2(1).
PMID: 39411357
Tight regulation of protein degradation pathways is essential for maintaining cardiac homeostasis. The goal of this work was to define the role of chaperone-mediated autophagy (CMA), in cardiomyocytes. CMA acts...
2.
Ghosh R, Fatahian A, Rouzbehani O, Hathaway M, Mosleh T, Vinod V, et al.
Cardiovasc Res
. 2024 Feb;
120(5):531-547.
PMID: 38332738
Aims: Heart failure due to ischaemic heart disease (IHD) is a leading cause of mortality worldwide. A major contributing factor to IHD-induced cardiac damage is hypoxia. Sequestosome 1 (p62) is...
3.
Jonnavithula A, Tandar M, Umar M, Orton S, Woodrum M, Mookherjee S, et al.
bioRxiv
. 2024 Jan;
PMID: 38168260
Objective: Pathologies including cardiovascular diseases, cancer, and neurological disorders are caused by the accumulation of misfolded / damaged proteins. Intracellular protein degradation mechanisms play a critical role in the clearance...
4.
Sun B, Rouzbehani O, Kramer R, Ghosh R, Perelli R, Atkins S, et al.
Circ Heart Fail
. 2023 Dec;
16(12):e010351.
PMID: 38113297
Background: PRDM16 plays a role in myocardial development through TGF-β (transforming growth factor-beta) signaling. Recent evidence suggests that loss of PRDM16 expression is associated with cardiomyopathy development in mice, although...
5.
Cho J, Ghosh R, Mookherjee S, Boudina S, Symons J
Aging (Albany NY)
. 2022 Dec;
14(23):9388-9392.
PMID: 36470665
During the aging process damaged/dysfunctional proteins and organelles accumulate and contribute to organ dysfunction. Luckily, there is a conserved intracellular process to reuse and recycle these dysregulated cellular components termed...
6.
Ghosh R, Gillaspie J, Campbell K, Symons J, Boudina S, Pattison J
Am J Physiol Cell Physiol
. 2022 May;
323(5):C1555-C1575.
PMID: 35584327
Chaperone-mediated autophagy (CMA) is a chaperone-dependent process of selective cytosolic protein turnover that targets specific proteins to lysosomes for degradation. Enhancing protein degradation mechanisms has been shown to be beneficial...
7.
Cho J, Park S, Ghosh R, Ly K, Ramous C, Thompson L, et al.
Aging Cell
. 2021 Sep;
20(10):e13467.
PMID: 34554626
Protein quality control mechanisms decline during the process of cardiac aging. This enables the accumulation of protein aggregates and damaged organelles that contribute to age-associated cardiac dysfunction. Macroautophagy is the...
8.
Ghosh R, Vinod V, Symons J, Boudina S
Cells
. 2020 Apr;
9(4).
PMID: 32290135
Cardiovascular disease (CVD) is the number one cause of death in the United States. Advancing age is a primary risk factor for developing CVD. Estimates indicate that 20% of the...
9.
Ghosh R, Pattison J
Oxid Med Cell Longev
. 2018 Mar;
2018:8602041.
PMID: 29576856
Cardiac diseases including hypertrophic and ischemic cardiomyopathies are increasingly being reported to accumulate misfolded proteins and damaged organelles. These findings have led to an increasing interest in protein degradation pathways,...
10.
Ghosh R, Goswami S, Feitoza L, Hammock B, Gomes A
Int J Cardiol
. 2016 Sep;
223:923-935.
PMID: 27589040
Background: One of the most common nonsteroidal anti-inflammatory drugs (NSAIDs) used worldwide, diclofenac (DIC), has been linked to increased risk of cardiovascular disease (CVD). The molecular mechanism(s) by which DIC...