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Rajendra Bhadane

Explore the profile of Rajendra Bhadane including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 93
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Recent Articles
1.
Inam W, Bhadane R, Yan J, Peurla M, Salo-Ahen O, Rosenholm J, et al.
Adv Colloid Interface Sci . 2025 Jan; 338:103400. PMID: 39823916
In the realm of hybrid nanomaterials, the construction of core/shell nanoparticles offer an effective strategy for encompassing a particle by a polymeric or other suitable material, leading to a nanocomposite...
2.
Sakari M, Bhadane R, Kumar S, Azevedo R, Malakoutikhah M, Masoumi A, et al.
J Biol Chem . 2024 Dec; 301(1):108106. PMID: 39706271
Enzyme promiscuity is the ability of an enzyme to catalyze an unexpected side reaction in addition to its main reaction. Here, we describe a biocatalytic process to produce nonhydrolyzable NAD+ ...
3.
Fu J, Han W, Zhang X, Sun Y, Bhadane R, Wei B, et al.
Research (Wash D C) . 2024 Sep; 2022:0014. PMID: 39290973
Oligonucleotide-based therapy has experienced remarkable development in the past 2 decades, but its broad applications are severely hampered by delivery vectors. Widely used viral vectors and lipid nanovectors are suffering...
4.
Daude R, Bhadane R, Shah J
Eur J Pharmacol . 2024 May; 975:176643. PMID: 38754539
Chronic diabetes mellitus is reported to be associated with acute kidney injury. The enzyme histone deacetylase-2 (HDAC-2) was found to be upregulated in diabetes-related kidney damage. Alpha-cyperone (α-CYP) is one...
5.
Yan J, Bhadane R, Ran M, Ma X, Li Y, Zheng D, et al.
Nat Commun . 2024 May; 15(1):3684. PMID: 38693181
The metal-nucleic acid nanocomposites, first termed metal-nucleic acid frameworks (MNFs) in this work, show extraordinary potential as functional nanomaterials. However, thus far, realized MNFs face limitations including harsh synthesis conditions,...
6.
Ganwir P, Bhadane R, Chaturbhuj G
Comput Biol Chem . 2024 Apr; 110:108074. PMID: 38678730
Sodium-glucose co-transporter 2 (SGLT2) is one of the important targets against type II diabetes mellitus. A typical SGLT2 inhibitor acts by inhibiting glucose reabsorption, thus lowering the blood glucose level....
7.
Mohanty S, Bhadane R, Kumar S
J Cell Biochem . 2023 Nov; 124(11):1870-1885. PMID: 37943107
Kinetochores are multi-protein assemblies present at the centromere of the human chromosome and play a crucial role in cellular mitosis. The CENP-T and CENP-W chains form a heterodimer, which is...
8.
Kling C, Sommer A, Almeida-Hernandez Y, Rodriguez A, Perez-Erviti J, Bhadane R, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37445740
Whooping cough is a severe childhood disease, caused by the bacterium , which releases pertussis toxin (PT) as a major virulence factor. Previously, we identified the human antimicrobial peptides α-defensin-1...
9.
Yadav S, Soni A, Tanwar O, Bhadane R, Besra G, Kawathekar N
ChemMedChem . 2023 May; 18(16):e202300099. PMID: 37246503
DprE1 is a crucial enzyme involved in the cell wall synthesis of Mycobacterium tuberculosis and a promising target for antituberculosis drug development. However, its unique structural characteristics for ligand binding...
10.
Bhadane R, Salo-Ahen O
Biomedicines . 2022 Nov; 10(11). PMID: 36359299
The ongoing pandemic caused by SARS-CoV-2 has gone through various phases. Since the initial outbreak, the virus has mutated several times, with some lineages showing even stronger infectivity and faster...