Raja B Singh
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Explore the profile of Raja B Singh including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
318
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Recent Articles
1.
Kaur H, Singh Y, Singh S, Singh R
Genome
. 2020 Oct;
64(4):355-371.
PMID: 33031715
The gut-brain axis (GBA) is a biochemical link that connects the central nervous system (CNS) and enteric nervous system (ENS). Clinical and experimental evidence suggests gut microbiota as a key...
2.
Prasher D, Greenway S, Singh R
Biochem Cell Biol
. 2019 May;
98(1):12-22.
PMID: 31112654
Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to society. It is recognized that environmental factors and individual lifestyles play important roles in disease susceptibility, but the...
3.
Singh R, Dandekar S, Elimban V, Gupta S, Dhalla N
Mol Cell Biochem
. 2016 Aug;
263(1):241-56.
PMID: 27520682
Cardiovascular disease is a major cause of death and thus a great deal of effort has been made in salvaging the diseased myocardium. Although various factors have been identified as...
4.
Singh R, Hryshko L, Freed D, Dhalla N
Can J Physiol Pharmacol
. 2012 Feb;
90(2):249-60.
PMID: 22316244
We tested whether the activation of proteolytic enzymes, calpain, and matrix metalloproteinases (MMPs) during ischemia-reperfusion (I/R) is mediated through oxidative stress. For this purpose, isolated rat hearts were subjected to...
5.
Singh R, Dhalla N
Can J Physiol Pharmacol
. 2010 Apr;
88(3):388-97.
PMID: 20393603
Depression in cardiac performance due to ischemia-reperfusion (I/R) injury is associated with the development of oxidative stress and decreased sarcolemmal (SL) Na+/K+-ATPase activity. Since both I/R and oxidative stress have...
6.
Singh R, Mengi S, Xu Y, Arneja A, Dhalla N
Exp Clin Cardiol
. 2009 Aug;
7(1):40-53.
PMID: 19644578
Atherosclerosis is a leading cause of mortality and morbidity in the western world. It has been recognized for over a century, and the understanding of its pathogenesis has undergone many...
7.
Singh R, Elimban V, Dhalla N
J Appl Physiol (1985)
. 2008 Oct;
105(6):1779-87.
PMID: 18832762
Isolated hearts subjected to ischemia-reperfusion (I/R) exhibit depressed cardiac performance and alterations in subcellular function. Since hearts perfused at constant flow (CF) and constant pressure (CP) show differences in their...
8.
Chohan P, Singh R, Dhalla N, Netticadan T
Cardiovasc Res
. 2005 Aug;
69(1):152-63.
PMID: 16125156
Objective: Earlier studies have shown that impaired cardiac contractility in ischemia reperfusion (IR) is associated with alterations in sarcoplasmic reticulum (SR) function. Impaired release of nitric oxide (NO) has been...
9.
Singh R, Dandekar S, Elimban V, Gupta S, Dhalla N
Mol Cell Biochem
. 2004 Nov;
263(1-2):241-56.
PMID: 15524184
Cardiovascular disease is a major cause of death and thus a great deal of effort has been made in salvaging the diseased myocardium. Although various factors have been identified as...
10.
Singh R, Chohan P, Dhalla N, Netticadan T
J Mol Cell Cardiol
. 2004 Jul;
37(1):101-10.
PMID: 15242740
Ca(2+) overload and free-radical injury are two mutually non-exclusive phenomena suggested to cause myocardial ischemia-reperfusion (IR)-induced contractile dysfunction; however, the mechanisms underlying their effects are not clear. One possible mechanism...