Rainer Macdonald
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Explore the profile of Rainer Macdonald including associated specialties, affiliations and a list of published articles.
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42
Citations
695
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Recent Articles
1.
Falak S, OSullivan D, Cleveland M, Cowen S, Busby E, Devonshire A, et al.
Clin Chem
. 2024 Dec;
71(3):378-386.
PMID: 39724302
Background: Nucleic acid amplification tests (NAATs) assist in the diagnosis of numerous infectious diseases. They are typically sensitive and specific and can be quickly developed and adapted. Far more challenging...
2.
Valiente E, Falak S, Kummrow A, Kammel M, Corman V, Macdonald R, et al.
BMC Res Notes
. 2023 Sep;
16(1):210.
PMID: 37697348
Objective: In routine clinical laboratories, severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is determined by reverse-transcription PCR (RT-PCR). In the COVID pandemic, a wide range of antigen detection tests were...
3.
Falak S, Macdonald R, Busby E, OSullivan D, Milavec M, Plauth A, et al.
Methods
. 2021 Mar;
201:34-40.
PMID: 33722693
Viral load monitoring in human immunodeficiency virus type 1 (HIV-1) infection is often performed using reverse transcription quantitative PCR (RT-qPCR) to observe response to treatment and identify the development of...
4.
Yang L, Wabnitz H, Gladytz T, Sudakou A, Macdonald R, Grosenick D
Biomed Opt Express
. 2020 Dec;
11(11):6570-6589.
PMID: 33282509
A novel methodology for solving the inverse problem of diffuse optics for two-layered structures is proposed to retrieve the absolute quantities of optical absorption and reduced scattering coefficients of the...
5.
Petersmann A, Macdonald R, Nauck M
J Diabetes Sci Technol
. 2020 Nov;
16(1):161-167.
PMID: 33218279
Background: Each measurement is subject to measurement uncertainty (MU). Consequently, each measurement of plasma glucose concentration used for diagnosis and monitoring of diabetes mellitus (DM) is affected. Although concepts and...
6.
Grote-Koska D, Klauke R, Kaiser P, Kramer U, Macdonald R, Lerche D, et al.
Clin Chem Lab Med
. 2020 Mar;
58(8):1314-1321.
PMID: 32167924
Background Total haemoglobin (Hb) concentration in blood belongs to the most requested measurands, and the HiCN method (hemiglobincyanide) is accepted as a reference. Although the reaction principle is clearly characterised,...
7.
Yang L, Wabnitz H, Gladytz T, Macdonald R, Grosenick D
Opt Express
. 2019 Nov;
27(19):26415-26431.
PMID: 31674524
A multivariate method integrating time and space resolved techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical absorption and scattering properties in tissues. The time-domain...
8.
Grosenick D, Wabnitz H, Macdonald R
Biomed Tech (Berl)
. 2018 Mar;
63(5):511-518.
PMID: 29494335
Optical imaging of biological tissue in vivo at multiple wavelengths in the near-infrared (NIR) spectral range can be achieved with picosecond time resolution at high sensitivity by time-correlated single photon...
9.
Di Sieno L, Wabnitz H, Pifferi A, Mazurenka M, Hoshi Y, Dalla Mora A, et al.
Rev Sci Instrum
. 2016 Apr;
87(3):035118.
PMID: 27036830
We present a system for non-contact time-resolved diffuse reflectance imaging, based on small source-detector distance and high dynamic range measurements utilizing a fast-gated single-photon avalanche diode. The system is suitable...
10.
Martelli F, Del Bianco S, Spinelli L, Cavalieri S, Di Ninni P, Binzoni T, et al.
J Biomed Opt
. 2015 Nov;
20(11):115001.
PMID: 26524677
In this work, we have tested the optimal estimation (OE) algorithm for the reconstruction of the optical properties of a two-layered liquid tissue phantom from time-resolved single-distance measurements. The OE...