Rainer Landgraf
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Explore the profile of Rainer Landgraf including associated specialties, affiliations and a list of published articles.
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102
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3996
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Recent Articles
1.
Pavlov D, Gorlova A, Bettendorff L, Kalueff A, Umriukhin A, Proshin A, et al.
Neurobiol Learn Mem
. 2020 Apr;
172:107227.
PMID: 32325189
Deficient learning and memory are well-established pathophysiologic features of depression, however, mechanisms of the enhanced learning of aversive experiences associated with this disorder are poorly understood. Currently, neurobiological mechanisms of...
2.
Neumann I, Landgraf R
J Neuroendocrinol
. 2019 Feb;
31(3):e12695.
PMID: 30748037
A short overview is provided of the last 30 years of oxytocin (and vasopressin) research performed in our laboratories, starting with attempts to monitor the release of this nonapeptide in...
3.
Chekmareva N, Umriukhin A, Landgraf R, Sotnikov S
Behav Neurosci
. 2019 Jan;
133(1):68-76.
PMID: 30688486
This study focused on genetically determined versus acquired factors in shaping anxiety-related behavior by combining cross-breeding and cross-fostering approaches. Via cross-breeding of HAB (high anxiety-related behavior) female and LAB (low...
4.
Sah A, Sotnikov S, Kharitonova M, Schmuckermair C, Diepold R, Landgraf R, et al.
Int J Neuropsychopharmacol
. 2019 Jan;
22(4):317-328.
PMID: 30668714
Background: Pathological anxiety originates from a complex interplay of genetic predisposition and environmental factors, acting via epigenetic mechanisms. Epigenetic processes that can counteract detrimental genetic risk towards innate high anxiety...
5.
Naik R, Sotnikov S, Diepold R, Iurato S, Markt P, Bultmann A, et al.
Transl Psychiatry
. 2018 Jan;
8(1):1.
PMID: 29317594
TMEM132D is a candidate gene, where risk genotypes have been associated with anxiety severity along with higher mRNA expression in the frontal cortex of panic disorder patients. Concurrently, in a...
6.
Zelena D, Pinter O, Balazsfi D, Langnaese K, Richter K, Landgraf R, et al.
Amino Acids
. 2015 Jun;
47(11):2245-53.
PMID: 26100541
The nonapeptide arginine vasopressin (AVP) has long been suggested to play an important role as a secretagogue for triggering the activity of the endocrine stress response. Most recent studies employed...
7.
Brenndorfer J, Altmann A, Widner-Andra R, Putz B, Czamara D, Tilch E, et al.
PLoS One
. 2015 May;
10(5):e0128465.
PMID: 26011321
Genomic copy number variants (CNVs) have been implicated in multiple psychiatric disorders, but not much is known about their influence on anxiety disorders specifically. Using next-generation sequencing (NGS) and two...
8.
Yen Y, Gassen N, Zellner A, Rein T, Landgraf R, Wotjak C, et al.
Front Behav Neurosci
. 2015 Apr;
9:67.
PMID: 25852508
Psychostimulants show therapeutic efficacy in the treatment of attention-deficit hyperactivity disorder (ADHD). It is generally assumed that they ameliorate ADHD symptoms via interfering with monoaminergic signaling. We combined behavioral pharmacology,...
9.
Dine J, Ionescu I, Avrabos C, Yen Y, Holsboer F, Landgraf R, et al.
PLoS One
. 2015 Apr;
10(4):e0120272.
PMID: 25830625
The neurobiological basis of pathological anxiety and the improvement of its pharmacological treatment are a matter of intensive investigation. Here, using electrophysiological techniques in brain slices from animals of the...
10.
Slattery D, Naik R, Grund T, Yen Y, Sartori S, Fuchsl A, et al.
J Neurosci
. 2015 Mar;
35(11):4599-613.
PMID: 25788677
Neuropeptide S (NPS) has generated substantial interest due to its anxiolytic and fear-attenuating effects in rodents, while a corresponding receptor polymorphism associated with increased NPS receptor (NPSR1) surface expression and...