Rafik M Ghobrial
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Explore the profile of Rafik M Ghobrial including associated specialties, affiliations and a list of published articles.
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98
Citations
2019
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Recent Articles
21.
Abdelrahim M, Victor D, Esmail A, Kodali S, Graviss E, Nguyen D, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35158918
Background: Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third most common cause of cancer-related mortality worldwide. Transarterial chemoembolization has shown survival benefits in patients with early...
22.
Kloc M, Uosef A, Wosik J, Kubiak J, Ghobrial R
Arch Virol
. 2022 Feb;
167(3):737-749.
PMID: 35102456
The actin cytoskeleton and actin-dependent molecular and cellular events are responsible for the organization of eukaryotic cells and their functions. Viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), depend...
23.
Wang Y, Xiao X, Kong G, Wen M, Wang G, Ghobrial R, et al.
Am J Transplant
. 2021 Oct;
22(2):414-426.
PMID: 34599765
T cells must be activated and become effectors first before executing allograft rejection, a process that is regulated by diverse signals and transcription factors. In this study, we studied the...
24.
Kodali S, Shetty A, Shekhar S, Victor D, Ghobrial R
J Clin Med
. 2021 Jun;
10(11).
PMID: 34072277
Cholangiocarcinoma is a tumor that arises as a result of differentiation of the cholangiocytes and can develop from anywhere in the biliary tree. Subtypes of cholangiocarcinoma are differentiated based on...
25.
Kloc M, Chanana P, Vaughn N, Uosef A, Kubiak J, Ghobrial R
Biology (Basel)
. 2021 Apr;
10(4).
PMID: 33916969
Actin is one of the most abundant proteins in eukaryotic cells. There are different pools of nuclear actin often undetectable by conventional staining and commercial antibodies used to identify cytoplasmic...
26.
Kloc M, Uosef A, Kubiak J, Ghobrial R
Biology (Basel)
. 2021 Apr;
10(3).
PMID: 33808658
Human placenta formation relies on the interaction between fused trophoblast cells of the embryo with uterine endometrium. The fusion between trophoblast cells, first into cytotrophoblast and then into syncytiotrophoblast, is...
27.
Hobeika M, Saharia A, Mobley C, Menser T, Nguyen D, Graviss E, et al.
Clin Transplant
. 2021 Apr;
35(6):e14304.
PMID: 33792971
Background: Careful donor-recipient matching and reduced ischemia times have improved outcomes following donation after circulatory death (DCD) liver transplantation (LT). This study examines a single-center experience with DCD LT including...
28.
Kloc M, Uosef A, Villagran M, Zdanowski R, Kubiak J, Wosik J, et al.
Biology (Basel)
. 2021 Jan;
10(2).
PMID: 33498417
The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1and and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all...
29.
Kloc M, Ghobrial R, Lipinska-Opalka A, Wawrzyniak A, Zdanowski R, Kalicki B, et al.
Cell Immunol
. 2020 Dec;
360:104259.
PMID: 33359760
Vitamin D regulates homeostasis, anti-microbial response, and inflammation. The vitamin D receptors are expressed in the macrophages and other immune cells, regulating the transcription of many different genes, including those...
30.
Kloc M, Uosef A, Kubiak J, Ghobrial R
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33352942
Tissue-resident macrophages and those conscripted from the blood/bone marrow are professional phagocytes. They play a role in tissue homeostasis, replacement, and healing, and are the first-line responders to microbial (viral,...