Rafi Mazor
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Explore the profile of Rafi Mazor including associated specialties, affiliations and a list of published articles.
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20
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291
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Recent Articles
11.
Pocock E, Alsaigh T, Mazor R, Schmid-Schonbein G
Vasc Cell
. 2014 Dec;
6(1):24.
PMID: 25520775
Chronic venous disease (CVD) has a range of clinical presentations, including tortuous, distended veins in lower extremities, increasing skin pigmentation, and in severe cases ulceration of the affected skin. Venous...
12.
Cohen-Mazor M, Mazor R, Kristal B, Sela S
Biomed Res Int
. 2014 May;
2014:459640.
PMID: 24877096
Aims: To test the hypothesis that primed PMNLs in blood of chronic kidney disease patients release the active form of elastase and cathepsin G causing degradation of vital proteins and...
13.
Mazor R, Alsaigh T, Shaked H, Altshuler A, Pocock E, Kistler E, et al.
J Biol Chem
. 2012 Nov;
288(1):598-607.
PMID: 23155052
Matrix metalloproteinase-1 (MMP-1) is a collagenase that is highly active in extracellular matrix and vascular remodeling, angiogenesis, and tumor progression. Vascular endothelial growth factor receptor-2 (VEGFR2), the main receptor for...
14.
Mazor R, Itzhaki O, Sela S, Yagil Y, Cohen-Mazor M, Yagil C, et al.
Hypertension
. 2010 Jan;
55(2):353-62.
PMID: 20065151
In the Sabra rat, oxidative stress (OS) and inflammation precede the development of hypertension. Inhibition of the phagocytic NADPH oxidase attenuates the rise in blood pressure. The present study was...
15.
Cohen-Mazor M, Sela S, Mazor R, Ilan N, Vlodavsky I, Rops A, et al.
Am J Physiol Heart Circ Physiol
. 2007 Nov;
294(2):H651-8.
PMID: 18032524
Patients on chronic hemodialysis (HD) are at high risk for developing atherosclerosis and cardiovascular complications. Heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is involved in...
16.
Mazor R, Kristal B, Cohen-Mazor M, Yagil C, Yagil Y, Sela S
J Hypertens
. 2007 Oct;
25(11):2249-56.
PMID: 17921819
Background: We previously showed that priming of the polymorphonuclear leukocyte (PMNL), inflammation and oxidative stress antecede the development of hypertension in the Sabra rat model of hypertension. The actual role...
17.
Mazor R, Shurtz-Swirski R, Farah R, Kristal B, Shapiro G, Dorlechter F, et al.
Atherosclerosis
. 2007 Sep;
197(2):937-43.
PMID: 17869258
Background: Oxidative stress (OS) and chronic inflammation are involved and contribute to the development of atherosclerosis. Primed polymorphonuclear leukocytes (PMNLs) are a possible source for superoxide radicals and inflammatory mediators,...
18.
Mazor R, Shurtz-Swirski R, Sela S, Shapiro G, Kristal B
Harefuah
. 2007 Jan;
145(12):900-3, 941.
PMID: 17220029
Background: In hypertensive patients, the polymorphonuclear leukocytes (PMNLs) are primed, concomitantly contributing to oxidative stress and chronic low-grade inflammation. Furthermore, in the Sabra rat model of salt-induced hypertension, priming of...
19.
Sela S, Shurtz-Swirski R, Cohen-Mazor M, Mazor R, Chezar J, Shapiro G, et al.
J Am Soc Nephrol
. 2005 Jul;
16(8):2431-8.
PMID: 15987755
This study characterizes the causal relationship between peripheral polymorphonuclear leukocyte (PMNL) priming, systemic oxidative stress (OS), and inflammation in patients with varying degrees of renal insufficiency (chronic kidney disease [CKD]...
20.
Sela S, Mazor R, Amsalam M, Yagil C, Yagil Y, Kristal B
Hypertension
. 2004 Sep;
44(5):764-9.
PMID: 15452031
Hypertension is accompanied by systemic oxidative stress, inflammation, and priming of peripheral polymorphonuclear leukocytes (PMNLs), yet the involvement of these factors in the pathophysiology of hypertension is incompletely understood. We...