Raelene Pickering
Overview
Explore the profile of Raelene Pickering including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
428
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0
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Recent Articles
1.
M Bader S, Cooney J, Sheerin D, Taiaroa G, Harty L, Davidson K, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(32):e2301689120.
PMID: 37523564
The diversity of COVID-19 disease in otherwise healthy people, from seemingly asymptomatic infection to severe life-threatening disease, is not clearly understood. We passaged a naturally occurring near-ancestral SARS-CoV-2 variant, capable...
2.
Pymm P, Adair A, Chan L, Cooney J, Mordant F, Allison C, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(19).
PMID: 33893175
Neutralizing antibodies are important for immunity against SARS-CoV-2 and as therapeutics for the prevention and treatment of COVID-19. Here, we identified high-affinity nanobodies from alpacas immunized with coronavirus spike and...
3.
Brennan E, Mohan M, McClelland A, de Gaetano M, Tikellis C, Marai M, et al.
Diabetes
. 2018 Sep;
67(12):2657-2667.
PMID: 30213823
Increasing evidence points to the fact that defects in the resolution of inflammatory pathways predisposes individuals to the development of chronic inflammatory diseases, including diabetic complications such as accelerated atherosclerosis....
4.
Thomas M, Woodward M, Li Q, Pickering R, Tikellis C, Poulter N, et al.
J Am Heart Assoc
. 2018 Jul;
7(13).
PMID: 29960985
Background: 8-Oxo-2'-deoxyguanosine (8-oxo-2'-dG) is a biomarker of oxidative DNA damage that is associated with cardiovascular disease and premature mortality in the general population. Although oxidative stress has a proven role...
5.
Brennan E, Mohan M, McClelland A, Tikellis C, Ziemann M, Kaspi A, et al.
J Am Soc Nephrol
. 2018 Mar;
29(5):1437-1448.
PMID: 29490938
The failure of spontaneous resolution underlies chronic inflammatory conditions, including microvascular complications of diabetes such as diabetic kidney disease. The identification of endogenously generated molecules that promote the physiologic resolution...
6.
Hagiwara S, Sourris K, Ziemann M, Tieqiao W, Mohan M, McClelland A, et al.
Diabetes
. 2018 Feb;
67(5):960-973.
PMID: 29449307
Signaling via the receptor of advanced glycation end products (RAGE)-though complex and not fully elucidated in the setting of diabetes-is considered a key injurious pathway in the development of diabetic...
7.
Sharma A, Yuen D, Huet O, Pickering R, Stefanovic N, Bernatchez P, et al.
Vascul Pharmacol
. 2017 Oct;
99:83.
PMID: 28993043
No abstract available.
8.
Brennan E, Wang B, McClelland A, Mohan M, Marai M, Beuscart O, et al.
Diabetes
. 2017 May;
66(8):2266-2277.
PMID: 28487436
The let-7 miRNA family plays a key role in modulating inflammatory responses. Vascular smooth muscle cell (SMC) proliferation and endothelial cell (EC) dysfunction are critical in the pathogenesis of atherosclerosis,...
9.
De Blasio M, Ramalingam A, Cao A, Prakoso D, Ye J, Pickering R, et al.
Eur J Pharmacol
. 2017 Apr;
807:12-20.
PMID: 28438648
Endoplasmic reticulum (ER) stress contributes to progression of diabetic nephropathy, which promotes end-stage renal failure in diabetic patients. This study was undertaken to investigate the actions of tempol and ramipril,...
10.
Sharma A, Yuen D, Huet O, Pickering R, Stefanovic N, Bernatchez P, et al.
Vascul Pharmacol
. 2015 Nov;
79:32-42.
PMID: 26569096
A critical early event in the pathogenesis of atherosclerosis is vascular inflammation leading to endothelial dysfunction (ED). Reactive oxygen species and inflammation are inextricably linked and declining antioxidant defense is...