Radoslav Savic
Overview
Explore the profile of Radoslav Savic including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
798
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Recent Articles
1.
Savic R, Yang J, Koplev S, An M, Patel P, OBrien R, et al.
Cell Rep
. 2023 Nov;
42(11):113371.
PMID: 37938972
Senescent cells are a major contributor to age-dependent cardiovascular tissue dysfunction, but knowledge of their in vivo cell markers and tissue context is lacking. To reveal tissue-relevant senescence biology, we...
2.
Readhead B, Hartley B, Eastwood B, Collier D, Evans D, Farias R, et al.
Nat Commun
. 2018 Nov;
9(1):4926.
PMID: 30451900
In the originally published version of this Article, the affiliation details for Eric E. Schadt and Radoslav Savic incorrectly omitted 'Sema4, a Mount Sinai venture, Stamford, Connecticut, USA'. This has...
3.
Readhead B, Hartley B, Eastwood B, Collier D, Evans D, Farias R, et al.
Nat Commun
. 2018 Oct;
9(1):4412.
PMID: 30356048
A lack of biologically relevant screening models hinders the discovery of better treatments for schizophrenia (SZ) and other neuropsychiatric disorders. Here we compare the transcriptional responses of 8 commonly used...
4.
Savic R, He X, Fiel I, Schuchman E
PLoS One
. 2013 Jun;
8(5):e65620.
PMID: 23724146
Background: Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the third leading cause of cancer death worldwide. The only approved systemic treatment for unresectable HCC is...
5.
Savic R, Schuchman E
Adv Cancer Res
. 2013 Jan;
117:91-115.
PMID: 23290778
Acid sphingomyelinase (ASM) is a lipid hydrolase that cleaves the sphingolipid, sphingomyelin, into ceramide. Mutations in the ASM gene (SMPD1) result in the rare lysosomal storage disorder, Niemann-Pick disease (NPD)....
6.
Lachenmayer A, Alsinet C, Savic R, Cabellos L, Toffanin S, Hoshida Y, et al.
Clin Cancer Res
. 2012 Jul;
18(18):4997-5007.
PMID: 22811581
Purpose: Hepatocellular carcinoma (HCC) is a heterogeneous cancer with active Wnt signaling. Underlying biologic mechanisms remain unclear and no drug targeting this pathway has been approved to date. We aimed...
7.
Minguez B, Hoshida Y, Villanueva A, Toffanin S, Cabellos L, Thung S, et al.
J Hepatol
. 2011 Jun;
55(6):1325-31.
PMID: 21703203
Background & Aims: Vascular invasion is a major predictor of tumor recurrence after surgical treatments for hepatocellular carcinoma (HCC). While macroscopic vascular invasion can be detected by radiological techniques, pre-operative...
8.
Toffanin S, Hoshida Y, Lachenmayer A, Villanueva A, Cabellos L, Minguez B, et al.
Gastroenterology
. 2011 Feb;
140(5):1618-28.e16.
PMID: 21324318
Background & Aims: Hepatocellular carcinoma (HCC) is a heterogeneous tumor that develops via activation of multiple pathways and molecular alterations. It has been a challenge to identify molecular classes of...
9.
Villanueva A, Hoshida Y, Toffanin S, Lachenmayer A, Alsinet C, Savic R, et al.
Clin Cancer Res
. 2010 Aug;
16(19):4688-94.
PMID: 20713493
Accurate prognosis prediction in oncology is critical. In patients with hepatocellular carcinoma (HCC), unlike most solid tumors, the coexistence of two life-threatening conditions, cancer and cirrhosis, makes prognostic assessments difficult....
10.
Villanueva A, Savic R, Llovet J
Cancer Cell
. 2009 Oct;
16(4):272-3.
PMID: 19800570
In this issue of Cancer Cell, Haybaeck et al. unravel the role of lymphotoxin pathway in the development of hepatocellular carcinoma (HCC). Aberrant activation of this cascade in mice livers...