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Radmila Terentyeva

Explore the profile of Radmila Terentyeva including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1596
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Recent Articles
1.
Pinckard K, Felix-Soriano E, Hamilton S, Terentyeva R, Baer L, Wright K, et al.
Mol Metab . 2024 Mar; 82:101914. PMID: 38479548
Objective: The intrauterine environment during pregnancy is a critical factor in the development of obesity, diabetes, and cardiovascular disease in offspring. Maternal exercise prevents the detrimental effects of a maternal...
2.
Clements R, Terentyeva R, Hamilton S, Janssen P, Roder K, Martin B, et al.
Basic Res Cardiol . 2023 May; 118(1):15. PMID: 37138037
Calcium transfer into the mitochondrial matrix during sarcoplasmic reticulum (SR) Ca release is essential to boost energy production in ventricular cardiomyocytes (VCMs) and match increased metabolic demand. Mitochondria from female...
3.
Bonilla I, Baine S, Pokrass A, Mariangelo J, Kalyanasundaram A, Bogdanov V, et al.
J Appl Physiol (1985) . 2023 Mar; 134(5):1287-1299. PMID: 36995910
Cardiac stromal interaction molecule 1 (STIM1), a key mediator of store-operated Ca entry (SOCE), is a known determinant of cardiomyocyte pathological growth in hypertrophic cardiomyopathy. We examined the role of...
4.
Tarasov M, Struckman H, Olgar Y, Miller A, Demirtas M, Bogdanov V, et al.
J Clin Invest . 2023 Feb; 133(7). PMID: 36821382
Calmodulin (CaM) plays critical roles in cardiomyocytes, regulating Na+ (NaV) and L-type Ca2+ channels (LTCCs). LTCC dysregulation by mutant CaMs has been implicated in action potential duration (APD) prolongation and...
5.
Hamilton S, Terentyeva R, Bogdanov V, Kim T, Perger F, Yan J, et al.
Circ Res . 2022 Jan; 130(5):711-724. PMID: 35086342
Background: Oxidative stress in cardiac disease promotes proarrhythmic disturbances in Ca homeostasis, impairing luminal Ca regulation of the sarcoplasmic reticulum (SR) Ca release channel, the RyR2 (ryanodine receptor), and increasing...
6.
Hamilton S, Terentyeva R, Perger F, Orengo B, Martin B, Gorr M, et al.
Am J Physiol Heart Circ Physiol . 2021 Aug; 321(4):H615-H632. PMID: 34415186
Cardiac dysfunction in heart failure (HF) and diabetic cardiomyopathy (DCM) is associated with aberrant intracellular Ca handling and impaired mitochondrial function accompanied with reduced mitochondrial calcium concentration (mito-[Ca]). Pharmacological or...
7.
Hamilton S, Terentyeva R, Clements R, Belevych A, Terentyev D
J Mol Cell Cardiol . 2021 Apr; 156:105-113. PMID: 33857485
Sudden cardiac death due to ventricular tachyarrhythmias remains the major cause of mortality in the world. Heart failure, diabetic cardiomyopathy, old age-related cardiac dysfunction and inherited disorders are associated with...
8.
Baine S, Bonilla I, Belevych A, Stepanov A, Dorn L, Terentyeva R, et al.
J Cell Mol Med . 2021 Mar; 25(10):4637-4648. PMID: 33755308
Heart failure (HF) is characterized by asymmetrical autonomic balance. Treatments to restore parasympathetic activity in human heart failure trials have shown beneficial effects. However, mechanisms of parasympathetic-mediated improvement in cardiac...
9.
Liu H, Zhao Y, Xie A, Kim T, Terentyeva R, Liu M, et al.
JACC Basic Transl Sci . 2021 Feb; 6(1):42-52. PMID: 33532665
Diabetes mellitus (DM) is associated with increased arrhythmia. Type 2 DM (T2DM) mice showed prolonged QT interval and increased ventricular arrhythmic inducibility, accompanied by elevated cardiac interleukin (IL)-1β, increased mitochondrial...
10.
Bronk P, Kim T, Polina I, Hamilton S, Terentyeva R, Roder K, et al.
Biophys J . 2020 Jul; 119(3):690-704. PMID: 32668235
Cardiac small conductance Ca-activated K (SK) channels are activated solely by Ca, but the SK current (I) is inwardly rectified. However, the impact of inward rectification in shaping action potentials...