Rada Massarwa
Overview
Explore the profile of Rada Massarwa including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
2271
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Recent Articles
1.
Bayerl J, Ayyash M, Shani T, Manor Y, Gafni O, Massarwa R, et al.
Cell Stem Cell
. 2021 Apr;
28(9):1549-1565.e12.
PMID: 33915080
Isolating human MEK/ERK signaling-independent pluripotent stem cells (PSCs) with naive pluripotency characteristics while maintaining differentiation competence and (epi)genetic integrity remains challenging. Here, we engineer reporter systems that allow the screening...
2.
Aguilera-Castrejon A, Oldak B, Shani T, Ghanem N, Itzkovich C, Slomovich S, et al.
Nature
. 2021 Mar;
593(7857):119-124.
PMID: 33731940
The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos...
3.
Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, et al.
Cell Stem Cell
. 2018 Dec;
24(2):328-341.e9.
PMID: 30554962
The epigenetic dynamics of induced pluripotent stem cell (iPSC) reprogramming in correctly reprogrammed cells at high resolution and throughout the entire process remain largely undefined. Here, we characterize conversion of...
4.
Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, et al.
Cell Stem Cell
. 2018 Aug;
23(3):412-425.e10.
PMID: 30122475
Mbd3, a member of nucleosome remodeling and deacetylase (NuRD) co-repressor complex, was previously identified as an inhibitor for deterministic induced pluripotent stem cell (iPSC) reprogramming, where up to 100% of...
5.
Manor Y, Massarwa R, Hanna J
Curr Opin Genet Dev
. 2015 Aug;
34:35-45.
PMID: 26291026
Pluripotency is first assembled within the inner-cell-mass of developing pre-implantation blastocysts, and is gradually reconfigured and dismantled during early post-implantation development, before overt differentiation into somatic lineages ensues. This transition...
6.
Maza I, Caspi I, Zviran A, Chomsky E, Rais Y, Viukov S, et al.
Nat Biotechnol
. 2015 Jun;
33(7):769-74.
PMID: 26098448
Somatic cells can be transdifferentiated to other cell types without passing through a pluripotent state by ectopic expression of appropriate transcription factors. Recent reports have proposed an alternative transdifferentiation method...
7.
Gafni O, Weinberger L, AlFatah Mansour A, Manor Y, Chomsky E, Ben-Yosef D, et al.
Nature
. 2015 Apr;
520(7549):710.
PMID: 25830888
No abstract available.
8.
Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
Geula S, Moshitch-Moshkovitz S, Dominissini D, AlFatah Mansour A, Kol N, Salmon-Divon M, et al.
Science
. 2015 Jan;
347(6225):1002-6.
PMID: 25569111
Naïve and primed pluripotent states retain distinct molecular properties, yet limited knowledge exists on how their state transitions are regulated. Here, we identify Mettl3, an N(6)-methyladenosine (m(6)A) transferase, as a...
9.
Xiao X, Mruk D, Tang E, Massarwa R, Mok K, Li N, et al.
PLoS Genet
. 2014 Jun;
10(6):e1004447.
PMID: 24967734
During spermatogenesis, the blood-testis barrier (BTB) segregates the adluminal (apical) and basal compartments in the seminiferous epithelium, thereby creating a privileged adluminal environment that allows post-meiotic spermatid development to proceed...
10.
Massarwa R, Ray H, Niswander L
Wiley Interdiscip Rev Dev Biol
. 2014 Jun;
3(1):59-68.
PMID: 24902834
The neural tube (NT), the embryonic precursor of the vertebrate brain and spinal cord, is generated by a complex and highly dynamic morphological process. In mammals, the initially flat neural...