Noa Novershtern
Overview
Explore the profile of Noa Novershtern including associated specialties, affiliations and a list of published articles.
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23
Citations
3408
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Recent Articles
1.
Oldak B, Wildschutz E, Bondarenko V, Comar M, Zhao C, Aguilera-Castrejon A, et al.
Nature
. 2023 Sep;
622(7983):562-573.
PMID: 37673118
The ability to study human post-implantation development remains limited owing to ethical and technical challenges associated with intrauterine development after implantation. Embryo-like models with spatially organized morphogenesis and structure of...
2.
Viukov S, Shani T, Bayerl J, Aguilera-Castrejon A, Oldak B, Sheban D, et al.
Stem Cell Reports
. 2022 Oct;
17(11):2484-2500.
PMID: 36270280
The recent derivation of human trophoblast stem cells (TSCs) from placental cytotrophoblasts and blastocysts opened opportunities for studying the development and function of the human placenta. Recent reports have suggested...
3.
Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, et al.
Cell
. 2022 Aug;
185(18):3290-3306.e25.
PMID: 35988542
In vitro cultured stem cells with distinct developmental capacities can contribute to embryonic or extraembryonic tissues after microinjection into pre-implantation mammalian embryos. However, whether cultured stem cells can independently give...
4.
Lasman L, Hanna J, Novershtern N
Epigenomes
. 2021 Dec;
4(1).
PMID: 34968239
The rising field of RNA modifications is stimulating massive research nowadays. mA, the most abundant mRNA modification is highly conserved during evolution. Through the last decade, the essential components of...
5.
Sheban D, Shani T, Maor R, Aguilera-Castrejon A, Mor N, Oldak B, et al.
Mol Cell
. 2021 Dec;
82(1):106-122.e9.
PMID: 34875212
The fidelity of the early embryonic program is underlined by tight regulation of the chromatin. Yet, how the chromatin is organized to prohibit the reversal of the developmental program remains...
6.
Bayerl J, Ayyash M, Shani T, Manor Y, Gafni O, Massarwa R, et al.
Cell Stem Cell
. 2021 Apr;
28(9):1549-1565.e12.
PMID: 33915080
Isolating human MEK/ERK signaling-independent pluripotent stem cells (PSCs) with naive pluripotency characteristics while maintaining differentiation competence and (epi)genetic integrity remains challenging. Here, we engineer reporter systems that allow the screening...
7.
Aguilera-Castrejon A, Oldak B, Shani T, Ghanem N, Itzkovich C, Slomovich S, et al.
Nature
. 2021 Mar;
593(7857):119-124.
PMID: 33731940
The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos...
8.
Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera-Castrejon A, Schneir D, et al.
Genes Dev
. 2020 Sep;
34(19-20):1373-1391.
PMID: 32943573
The N6-methyladenosine (mA) modification is the most prevalent post-transcriptional mRNA modification, regulating mRNA decay and splicing. It plays a major role during normal development, differentiation, and disease progression. The modification...
9.
Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, et al.
Cell Stem Cell
. 2018 Dec;
24(2):328-341.e9.
PMID: 30554962
The epigenetic dynamics of induced pluripotent stem cell (iPSC) reprogramming in correctly reprogrammed cells at high resolution and throughout the entire process remain largely undefined. Here, we characterize conversion of...
10.
Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, et al.
Cell Stem Cell
. 2018 Aug;
23(3):412-425.e10.
PMID: 30122475
Mbd3, a member of nucleosome remodeling and deacetylase (NuRD) co-repressor complex, was previously identified as an inhibitor for deterministic induced pluripotent stem cell (iPSC) reprogramming, where up to 100% of...