Rachel Harland
Overview
Explore the profile of Rachel Harland including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
51
Followers
0
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Related Specialties
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Top 10 Co-Authors
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Recent Articles
1.
Cockerill G, Angell R, Bedernjak A, Chuckowree I, Fraser I, Gascon-Simorte J, et al.
J Med Chem
. 2021 Mar;
64(7):3658-3676.
PMID: 33729773
RV521 is an orally bioavailable inhibitor of respiratory syncytial virus (RSV) fusion that was identified after a lead optimization process based upon hits that originated from a physical property directed...
2.
DeVincenzo J, Tait D, Efthimiou J, Mori J, Kim Y, Thomas E, et al.
Antimicrob Agents Chemother
. 2019 Nov;
64(2).
PMID: 31712214
Effective treatments for respiratory syncytial virus (RSV) infection are lacking. Here, we report a human proof-of-concept study for RV521, a small-molecule antiviral inhibitor of the RSV-F protein. In this randomized,...
3.
Hider R, Kong X, Abbate V, Harland R, Conlon K, Luker T
Dalton Trans
. 2015 Feb;
44(11):5197-204.
PMID: 25687725
Following a systematic search of desferrithiocin analogs, a polyether derivative, deferitazole (formerly FBS0701), has entered into phase 1 and 2 clinical trials with promising biological properties. However, until now, detailed...