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Rachael Keating

Explore the profile of Rachael Keating including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1069
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Recent Articles
11.
Kedzierska K, Stambas J, Jenkins M, Keating R, Turner S, Doherty P
Proc Natl Acad Sci U S A . 2007 May; 104(23):9782-7. PMID: 17522251
The rapid recall of influenza virus-specific CD8(+) T cell effector function is protective, although our understanding of T cell memory remains incomplete. Recent debate has focused particularly on the CD62L...
12.
Thomas P, Brown S, Keating R, Yue W, Morris M, So J, et al.
J Immunol . 2007 Feb; 178(5):3091-8. PMID: 17312156
Influenza A virus-specific CD8+ T cell responses in H2(b) mice are characterized by reproducible hierarchies. Compensation by the D(b)PB1-F2(62) epitope is apparent following infection with a variant H3N2 virus engineered...
13.
Keating R, Yue W, Rutigliano J, So J, Olivas E, Thomas P, et al.
J Immunol . 2007 Feb; 178(5):2737-45. PMID: 17312116
Influenza A virus infection of C57BL/6 mice is a well-characterized model for studying CD8+ T cell-mediated immunity. Analysis of primary and secondary responses showed that the liver is highly enriched...
14.
Huber V, McKeon R, Brackin M, Miller L, Keating R, Brown S, et al.
Clin Vaccine Immunol . 2006 Sep; 13(9):981-90. PMID: 16960108
Vaccination represents the most effective form of protection against influenza infection. While neutralizing antibodies are typically measured as a correlate of vaccine-induced protective immunity against influenza, nonneutralizing antibodies may contribute...
15.
Thomas P, Keating R, Hulse-Post D, Doherty P
Emerg Infect Dis . 2006 Feb; 12(1):48-54. PMID: 16494717
Current vaccine strategies against influenza focus on generating robust antibody responses. Because of the high degree of antigenic drift among circulating influenza strains over the course of a year, vaccine...
16.
Cornish A, Keating R, Kyparissoudis K, Smyth M, Carbone F, Godfrey D
Immunol Cell Biol . 2005 Nov; 84(1):13-9. PMID: 16277640
NKT cells are a minor subset of T cells that have important roles in controlling immune responses in disease states including cancer, autoimmunity and pathogenic infections. In contrast to conventional...
17.
Crowe N, Coquet J, Berzins S, Kyparissoudis K, Keating R, Pellicci D, et al.
J Exp Med . 2005 Nov; 202(9):1279-88. PMID: 16275765
We showed previously that NKT cell-deficient TCR Jalpha18(-/-) mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor surveillance can be restored by adoptive transfer of WT liver-derived...
18.
Pellicci D, Hammond K, Coquet J, Kyparissoudis K, Brooks A, Kedzierska K, et al.
J Immunol . 2005 Sep; 175(7):4416-25. PMID: 16177083
NKT cells are typically defined as CD1d-dependent T cells that carry an invariant TCR alpha-chain and produce high levels of cytokines. Traditionally, these cells were defined as NK1.1+ T cells,...
19.
Crowe N, Uldrich A, Kyparissoudis K, Hammond K, Hayakawa Y, Sidobre S, et al.
J Immunol . 2003 Oct; 171(8):4020-7. PMID: 14530322
NKT cells are enigmatic lymphocytes that respond to glycolipid Ags presented by CD1d. Although they are key immunoregulatory cells, with a critical role in immunity to cancer, infection, and autoimmune...