Rachael E Hawtin
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Explore the profile of Rachael E Hawtin including associated specialties, affiliations and a list of published articles.
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17
Citations
358
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Recent Articles
1.
Curtis J, Emery P, Downie B, Zhong Y, Liu J, Han L, et al.
Rheumatol Ther
. 2023 Dec;
11(1):177-189.
PMID: 38057656
Objectives: To assess cigarette smoking's effects on efficacy of the preferential Janus kinase (JAK) 1 inhibitor filgotinib and drug persistence in patients with rheumatoid arthritis (RA). Methods: Efficacy in non-smokers,...
2.
Ptacek J, Hawtin R, Sun D, Louie B, Evensen E, Mittleman B, et al.
PLoS One
. 2021 Jan;
16(1):e0244187.
PMID: 33444321
Rheumatoid arthritis (RA) is a systemic and incurable autoimmune disease characterized by chronic inflammation in synovial lining of joints. To identify the signaling pathways involved in RA, its disease activity,...
3.
Formenti S, Hawtin R, Dixit N, Evensen E, Lee P, Goldberg J, et al.
J Immunother Cancer
. 2019 Jul;
7(1):177.
PMID: 31296256
Background: We previously reported the results of a multicentric prospective randomized trial of chemo-refractory metastatic breast cancer patients testing the efficacy of two doses of TGFβ blockade during radiotherapy. Despite...
4.
5.
Rosen D, Leung L, Louie B, Cordeiro J, Conroy A, Shapira I, et al.
J Transl Med
. 2014 Jun;
12:184.
PMID: 24965603
Background: Homologous recombination repair (HRR) pathway deficiencies have significant implications for cancer predisposition and treatment strategies. Improved quantitative methods for functionally characterizing these deficiencies are required to accurately identify patients...
6.
Longo D, Louie B, Ptacek J, Friedland G, Evensen E, Putta S, et al.
J Transl Med
. 2014 Jun;
12:178.
PMID: 24952610
Background: Single-cell network profiling (SCNP) is a multiparametric flow cytometry-based approach that simultaneously measures evoked signaling in multiple cell subsets. Previously, using the SCNP approach, age-associated immune signaling responses were...
7.
Longo D, Louie B, Wang E, Pos Z, Marincola F, Hawtin R, et al.
Am J Clin Exp Immunol
. 2013 Jul;
1(1):1-11.
PMID: 23885311
Single cell network profiling (SCNP) is a multi-parameter flow cytometry based approach that allows for the simultaneous interrogation of intracellular signaling pathways in multiple cell subpopulations within heterogeneous tissues, without...
8.
Cesano A, Putta S, Rosen D, Cohen A, Gayko U, Mathi K, et al.
PLoS One
. 2013 Feb;
8(2):e56714.
PMID: 23431389
FMS-like tyrosine kinase 3 receptor (FLT3) internal tandem duplication (ITD) mutations result in constitutive activation of this receptor and have been shown to increase the risk of relapse in patients...
9.
Rosen D, Harrington K, Cordeiro J, Leung L, Putta S, Lacayo N, et al.
PLoS One
. 2013 Jan;
8(1):e53518.
PMID: 23320091
Gemtuzumab ozogamicin (GO), an immunoconjugate between an anti-CD33 antibody and a calicheamicin-γ(1) derivative, induces remissions and improves survival in a subset of patients with acute myeloid leukemia (AML). As the...
10.
Cesano A, Perbellini O, Evensen E, Chu C, Cioffi F, Ptacek J, et al.
Haematologica
. 2012 Nov;
98(4):626-34.
PMID: 23144194
While many prognostic markers in B-cell chronic lymphocytic leukemia provide insight into the biology of the disease, few have been demonstrated to be useful in the daily management of patients....