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Rabab S Hamad

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Articles 33
Citations 50
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Recent Articles
11.
Elmorsy E, Saber S, Hamad R, Abdel-Reheim M, El-Kott A, Alshehri M, et al.
Eur J Pharm Sci . 2024 Jul; 200:106849. PMID: 38992452
Doxorubicin (DOX) is an anthracycline chemotherapy drug widely employed in the treatment of various cancers, known for its potent antineoplastic properties but often associated with dose-dependent cardiotoxicity, limiting its clinical...
12.
Cavalu S, Saber S, Amer A, Hamad R, Abdel-Reheim M, Elmorsy E, et al.
FASEB J . 2024 Jul; 38(13):e23813. PMID: 38976162
Beta-blockers are commonly used medications that antagonize β-adrenoceptors, reducing sympathetic nervous system activity. Emerging evidence suggests that beta-blockers may also have anticancer effects and help overcome drug resistance in cancer...
13.
Hasan A, Cavalu S, Saber S, Doghish A, Hamad R, Abdel-Reheim M, et al.
Life Sci . 2024 Jun; 351:122791. PMID: 38848936
Sorafenib is a multikinase inhibitor employed for managing hepatocellular carcinoma (HCC). The emergence of sorafenib resistance presents an obstacle to its therapeutic efficacy. One notable approach to overcoming sorafenib resistance...
14.
Cavalu S, Abdelhamid A, Saber S, Elmorsy E, Hamad R, Abdel-Reheim M, et al.
FASEB J . 2024 Jun; 38(11):e23734. PMID: 38847486
The cell cycle is tightly regulated to ensure controlled cell proliferation. Dysregulation of the cell cycle machinery is a hallmark of cancer that leads to unchecked growth. This review comprehensively...
15.
Elmorsy E, Saber S, Kira A, Alghasham A, Abdel-Hamed M, Amer M, et al.
Front Pharmacol . 2024 May; 15:1377980. PMID: 38808257
Liver fibrosis is a disease with a great global health and economic burden. Existing data highlights itraconazole (ITRCZ) as a potentially effective anti-fibrotic therapy. However, ITRCZ effect is hindered by...
16.
Mohammed O, Youssef M, Doghish A, Hamad R, Abdel-Reheim M, Alghamdi M, et al.
Eur J Pharm Sci . 2024 May; 198:106792. PMID: 38714237
Non-alcoholic steatohepatitis (NASH) is characterized by liver inflammation, fat accumulation, and collagen deposition. Due to the limited availability of effective treatments, there is a pressing need to develop innovative strategies....
17.
Cavalu S, Saber S, Hamad R, Abdel-Reheim M, Elmorsy E, Youssef M
Front Cell Neurosci . 2024 May; 18:1336145. PMID: 38699177
The orexins, also referred to as hypocretins, are neuropeptides that originate from the lateral hypothalamus (LH) region of the brain. They are composed of two small peptides, orexin-A, and orexin-B,...
18.
Abdelhady R, Saber S, Abdel-Reheim M, Alamri M, Alfaifi J, Adam M, et al.
Front Pharmacol . 2024 Mar; 15:1382529. PMID: 38545556
[This corrects the article DOI: 10.3389/fphar.2023.1239025.].
19.
Abdelhady R, Mohammed O, Doghish A, Hamad R, Abdel-Reheim M, Alamri M, et al.
FASEB J . 2024 Feb; 38(4):e23480. PMID: 38354025
Accumulating evidence suggests that dysregulation of FOXO3a plays a significant role in the progression of various malignancies, including hepatocellular carcinoma (HCC). FOXO3a inactivation, driven by oncogenic stimuli, can lead to...
20.
Altaf N, Ur Rehman N, Karim N, Khan I, Ahsan Halim S, Alotaibi B, et al.
Neurochem Res . 2024 Jan; 49(4):980-997. PMID: 38170385
Diabetic neuropathic pain is one of the most devasting disorders of peripheral nervous system. The loss of GABAergic inhibition is associated with the development of painful diabetic neuropathy. The current...