R W Roberts
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Explore the profile of R W Roberts including associated specialties, affiliations and a list of published articles.
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54
Citations
1016
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Recent Articles
1.
Barrick J, Takahashi T, Ren J, Xia T, Roberts R
Proc Natl Acad Sci U S A
. 2001 Oct;
98(22):12374-8.
PMID: 11675487
RNA loops that adopt a characteristic GNRA "tetraloop" fold are common in natural RNAs. Here, we have used in vitro selection by means of mRNA-peptide fusions to select peptides that...
2.
Thorsen T, Roberts R, Arnold F, Quake S
Phys Rev Lett
. 2001 May;
86(18):4163-6.
PMID: 11328121
Spatiotemporal pattern formation occurs in a variety of nonequilibrium physical and chemical systems. Here we show that a microfluidic device designed to produce reverse micelles can generate complex, ordered patterns...
3.
Barrick J, Takahashi T, Balakin A, Roberts R
Methods
. 2001 Mar;
23(3):287-93.
PMID: 11243841
We have been working to apply in vitro selection to isolate novel RNA-binding peptides. To do this, we use mRNA-protein fusions, peptides covalently attached to their own mRNA. Here, we...
4.
Liu R, Barrick J, Szostak J, Roberts R
Methods Enzymol
. 2000 Jul;
318:268-93.
PMID: 10889994
No abstract available.
5.
Roberts R, Ja W
Curr Opin Struct Biol
. 1999 Aug;
9(4):521-9.
PMID: 10449375
For almost a decade, in vitro selection experiments have been used to isolate novel nucleic acids, peptides and proteins according to their function. Selection experiments have altered our perception of...
6.
Roberts R
Curr Opin Chem Biol
. 1999 Jun;
3(3):268-73.
PMID: 10359713
Both chemists and biochemists have great interest in creating peptides and proteins with desired structure, recognition and catalytic properties. Recently, two techniques have been developed that afford functional selection of...
7.
Roberts R, Szostak J
Proc Natl Acad Sci U S A
. 1997 Nov;
94(23):12297-302.
PMID: 9356443
Covalent fusions between an mRNA and the peptide or protein that it encodes can be generated by in vitro translation of synthetic mRNAs that carry puromycin, a peptidyl acceptor antibiotic,...
8.
Roberts R, Crothers D
J Mol Biol
. 1996 Jul;
260(2):135-46.
PMID: 8764396
We report a study of the physical properties of oligonucleotide intramolecular Pyr.Pur.Pyr triplexes modeled after H-form DNA. The experiments utilized a set of palindromic pyrimidine strands which form triplexes when...
9.
Roberts R, Crothers D
Proc Natl Acad Sci U S A
. 1996 Apr;
93(9):4320-5.
PMID: 8633063
We present rules that allow one to predict the stability of DNA pyrimidine.purine.pyrimidine (Y.R.Y) triple helices on the basis of the sequence. The rules were derived from van't Hoff analysis...
10.
Carter B, Frohlich E, ELLIOTT W, Moore M, Mann R, Roberts R
Arch Fam Med
. 1994 Jun;
3(6):528-36.
PMID: 7915943
Numerous factors may influence an individual patient's response to antihypertensive therapy. The physician should select therapy that is more likely to effectively control the patient's blood pressure. In addition to...