R W Gelling
Overview
Explore the profile of R W Gelling including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
340
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Recent Articles
1.
Akesson L, Gelling R, Jensen R, Ogimoto K, Fuller J, Pefley R, et al.
Exp Clin Endocrinol Diabetes
. 2008 May;
116(8):475-80.
PMID: 18465680
Aim: The BB rat model of type 1 diabetes exhibits altered body weight gain and body temperature regulation prior to hyperglycemia onset, implying the existence of as yet unidentified biomarkers...
2.
Gelling R, Du X, Dichmann D, Romer J, Huang H, Cui L, et al.
Proc Natl Acad Sci U S A
. 2003 Jan;
100(3):1438-43.
PMID: 12552113
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic alpha cells in response to low blood glucose. To examine the role of glucagon in glucose homeostasis, mice were generated...
3.
Hinke S, Manhart S, Pamir N, DEMUTH H, Gelling R, PEDERSON R, et al.
Biochim Biophys Acta
. 2001 May;
1547(1):143-55.
PMID: 11343800
The incretins are a class of hormones released from the small bowel that act on the endocrine pancreas to potentiate insulin secretion in a glucose-dependent manner. Due to the requirement...
4.
Wheeler M, Gelling R, Hinke S, Tu B, PEDERSON R, Lynn F, et al.
J Biol Chem
. 1999 Aug;
274(35):24593-601.
PMID: 10455124
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone involved in the regulation of insulin secretion. In non-insulin-dependent diabetes mellitus insulin responses to GIP are blunted, possibly due to altered signal...
5.
Gelling R, Wheeler M, Xue J, Gyomorey S, Nian C, PEDERSON R, et al.
Endocrinology
. 1997 Jun;
138(6):2640-3.
PMID: 9165060
The receptors for the two structurally related insulinotropic hormones Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) share approximately 40% sequence identity and demonstrate complete specificity for their endogenous ligands,...
6.
Gelling R, Coy D, PEDERSON R, Wheeler M, Hinke S, Kwan T, et al.
Regul Pept
. 1997 Apr;
69(3):151-4.
PMID: 9226399
GIP (Glucose-dependent Insulinotropic Polypeptide) is an important regulator of insulin secretion. The effects of truncated forms of the peptide, GIP(10-30), GIP(6-30amide) and GIP(7-30), on binding of 125I-GIP(1-42) to GIP receptors...
7.
Schieldrop P, Gelling R, Elliot R, Hewitt J, Kieffer T, McIntosh C, et al.
Biochim Biophys Acta
. 1996 Aug;
1308(2):111-3.
PMID: 8764827
A 537 base pair cDNA clone for murine GIP has been isolated. The elucidated sequence encodes an open reading frame of 432 base pairs which codes for a 144 amino...
8.
McIntosh C, Wheeler M, Gelling R, Brown J, PEDERSON R
Acta Physiol Scand
. 1996 Jul;
157(3):361-5.
PMID: 8830895
No abstract available.
9.
Wheeler M, Gelling R, McIntosh C, Georgiou J, Brown J, PEDERSON R
Endocrinology
. 1995 Oct;
136(10):4629-39.
PMID: 7664683
Incretins are endogenous peptides released from the gastrointestinal tract into the circulation during a meal that potentiate glucose-stimulated insulin secretion. At present, there are two established incretins: glucose-dependent insulinotropic polypeptide...