R W Dutton
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Explore the profile of R W Dutton including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
3318
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Recent Articles
1.
Swain S, Dutton R
Immunol Today
. 2014 Oct;
1(3):61-5.
PMID: 25289764
The study of cell-surface markers has permitted the dissection of lymphocyte populations into subsets and made possible many of the current ideas about how cells interact to produce an immune...
2.
Raidt D, Mishell R, Dutton R
J Exp Med
. 2009 Oct;
128(4):681-98.
PMID: 19867303
Cell suspensions from the spleens of normal mice or mice injected with sheep erythrocytes were separated on a discontinous bovine serum albumin density gradient. Four bands or subpopulations were obtained...
3.
Dobrzanski M, Reome J, Dutton R
J Immunol
. 2001 Jun;
167(1):424-34.
PMID: 11418679
Type 2 CD8 T cells (Tc2) secrete IL-4 and IL-5 and display perforin-dependent cytolysis in vitro. Using an OVA-transfected B16-melanoma model, we show that tumor-reactive Tc2 effector cells accumulated at...
4.
Helmich B, Dutton R
J Immunol
. 2001 May;
166(11):6500-8.
PMID: 11359800
We had previously examined the factors that regulate the response of OVA-specific TCR-transgenic CD8 T cells to the B16 OVA melanoma, growing as lung metastases. We examine here whether the...
5.
Hogan R, Usherwood E, Zhong W, Roberts A, Dutton R, Harmsen A, et al.
J Immunol
. 2001 Feb;
166(3):1813-22.
PMID: 11160228
The poor correlation between cellular immunity to respiratory virus infections and the numbers of memory CD8(+) T cells in the secondary lymphoid organs suggests that there may be additional reservoirs...
6.
Wiley J, Cerwenka A, Harkema J, Dutton R, Harmsen A
Am J Pathol
. 2001 Jan;
158(1):119-30.
PMID: 11141485
This study examined the inflammation, lung function impairment, and immune protection associated with either wild-type or interferon (IFN)-gamma-deficient Tc1- or Tc2-CD8 effector cells responding to influenza pneumonia. The adoptive transfer...
7.
Dobrzanski M, Reome J, Dutton R
Clin Immunol
. 2001 Jan;
98(1):70-84.
PMID: 11141329
Type 1 cytolytic CD8 effector T cells (Tc1) characteristically secrete IFN-gamma. Using an OVA-transfected B16 melanoma lung tumor model, we show that OVA Ag-specific Tc1 cells mediate a reduction in...
8.
Reome J, Johnston D, Helmich B, Morgan T, Dutton R
J Immunol
. 2000 Oct;
165(8):4226-30.
PMID: 11035055
We have determined the in vivo effect of 5-bromodeoxyuridine (BrdU) administered to mice in the drinking water for various lengths of time on the performance of T and B lymphocytes...
9.
Dobrzanski M, Reome J, Dutton R
J Immunol
. 2000 Jan;
164(2):916-25.
PMID: 10623840
Cytolytic CD8+ effector cells fall into two subpopulations based on cytokine secretion. Type 1 CD8+ T cells (Tc1) secrete IFN-gamma, whereas type 2 CD8+ T cells (Tc2) secrete IL-4, IL-5,...
10.
Wang K, Dutton R, Taylor C
IEEE Eng Med Biol Mag
. 1999 Nov;
18(6):33-9.
PMID: 10576070
No abstract available.