R V Rajotte
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Explore the profile of R V Rajotte including associated specialties, affiliations and a list of published articles.
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226
Citations
3148
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Recent Articles
1.
Warnock G, Rajotte R
Can Fam Physician
. 2011 Jan;
38:1655-60.
PMID: 21221366
Transplantation of insulin-producing tissue offers a physiologic approach to restoration of glycemic control. Whereas transplantation of vascularized pancreatic grafts has recently achieved encouraging results, pancreatic islet cell transplantation holds the...
2.
Eshpeter A, Jiang J, Au M, Rajotte R, Lu K, Lebkowski J, et al.
Cell Prolif
. 2008 Dec;
41(6):843-858.
PMID: 19040565
Objectives: Islet-like clusters (ILCs), differentiated from human embryonic stem cells (hESCs), were characterized both before and after transplantation under the kidney capsule of streptozotocin-induced diabetic immuno-incompetent mice. Materials And Methods:...
3.
Diabetes induces rapid suppression of adaptive immunity followed by homeostatic T-cell proliferation
Luo B, Chan W, Lord S, Nanji S, Rajotte R, Shapiro A, et al.
Scand J Immunol
. 2007 Jan;
65(1):22-31.
PMID: 17212763
Surprisingly, the effect of acute diabetes on immunity has not been examined in detail. We, herein, show for the first time that untreated acute diabetes causes rapid lymphopenia followed by...
4.
Korbutt G, Mallett A, Ao Z, Flashner M, Rajotte R
Diabetologia
. 2004 Nov;
47(10):1810-8.
PMID: 15517151
Aims/hypothesis: The aim of this study was to determine whether a simple alginate capsule can prolong islet survival and function during long-term tissue culture. We also wanted to observe the...
5.
Street C, Lakey J, Seeberger K, Helms L, Rajotte R, Shapiro A, et al.
J Endocrinol
. 2004 Feb;
180(2):213-25.
PMID: 14765974
The discovery of a pancreatic adult stem cell would have significant implications for cell-based replacement therapies for type 1 diabetes mellitus. Nestin, a marker for neural precursor cells, has been...
6.
Dufour J, Hemendinger R, Halberstadt C, Gores P, Emerich D, Korbutt G, et al.
Gene Ther
. 2004 Jan;
11(8):694-700.
PMID: 14724669
The immunoprotective nature of the testis has led to numerous investigations for its ability to protect cellular grafts. Sertoli cells (SCs) are at least partially responsible for this immunoprotective environment...
7.
Rayat G, Rajotte R, Hering B, Binette T, Korbutt G
J Endocrinol
. 2003 Apr;
177(1):127-35.
PMID: 12697044
The expression of Galalpha-(1,3)Gal (alphaGal) on porcine islet cells remains controversial. Several groups have reported that porcine islet endocrine cells do not express alphaGal while we have shown in neonatal...
8.
Lu W, Lakey J, Juang J, Hsu B, Rajotte R
Transplant Proc
. 2003 Feb;
35(1):488-9.
PMID: 12591498
No abstract available.
9.
Lu W, Lakey J, Juang J, Hsu B, Rajotte R
Transplant Proc
. 2002 Nov;
34(7):2700-1.
PMID: 12431580
No abstract available.
10.
Lakey J, Suarez-Pinzon W, Strynadka K, Korbutt G, Rajotte R, Mabley J, et al.
Lab Invest
. 2001 Dec;
81(12):1683-92.
PMID: 11742038
The proinflammatory cytokines, interleukin-1beta (IL-1beta), tumor necrosis factor alpha (TNFalpha), and interferon gamma (IFNgamma), are cytotoxic to pancreatic islet beta cells, possibly by inducing nitric oxide and/or oxygen radical production...