R Tynes
Overview
Explore the profile of R Tynes including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
101
Followers
0
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Recent Articles
1.
Keck D, Tynes R
Appl Opt
. 2010 Feb;
11(7):1502-6.
PMID: 20119177
The attainment of 20-dB/km attenuation in experimental single-mode glass optical waveguides has spurred interest in their use for optical communications. The primary wavelength region of interest is in the red...
2.
Vickers A, ZOLLINGER M, Dannecker R, Tynes R, Heitz F, Fischer V
Drug Metab Dispos
. 2001 Sep;
29(10):1269-76.
PMID: 11560869
Tegaserod is a selective 5-HT(4) receptor partial agonist with promotile activity in the gastrointestinal tract. This study was designed to describe the metabolic pathways of tegaserod in the human liver...
3.
Eckhardt U, Schroeder A, Stieger B, HOCHLI M, Landmann L, Tynes R, et al.
Am J Physiol
. 1999 Apr;
276(4):G1037-42.
PMID: 10198348
The rat liver organic anion transporting polypeptide (Oatp1) has been extensively characterized mainly in the Xenopus laevis expression system as a polyspecific carrier transporting organic anions (bile salts), neutral compounds,...
4.
Fischer V, Rodriguez-Gascon A, Heitz F, Tynes R, Hauck C, Cohen D, et al.
Drug Metab Dispos
. 1998 Aug;
26(8):802-11.
PMID: 9698296
The metabolism of valspodar (PSC 833; PSC), which is developed as a multidrug resistance-reversing agent, was investigated to assess the potential for drug-drug interactions and the pharmacological activity of major...
5.
Schroeder A, Eckhardt U, Stieger B, Tynes R, Schteingart C, Hofmann A, et al.
Am J Physiol
. 1998 Mar;
274(2):G370-5.
PMID: 9486191
It has been proposed that the hepatocellular Na(+)-dependent bile salt uptake system exhibits a broad substrate specificity in intact hepatocytes. In contrast, recent expression studies in mammalian cell lines have...
6.
Fischer V, Vickers A, Heitz F, Mahadevan S, Baldeck J, Minery P, et al.
Drug Metab Dispos
. 1994 Mar;
22(2):269-74.
PMID: 8013282
Tropisetron and ondansetron, which are potent and selective 5-hydroxytryptamine (5-HT3) receptor antagonists, were both metabolized by human liver microsomes to several metabolites. These metabolites include the major metabolites found in...