R S Hare
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Explore the profile of R S Hare including associated specialties, affiliations and a list of published articles.
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53
Citations
1138
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Recent Articles
1.
Shaw K, Sabatelli F, Naples L, Mann P, Hare R, Miller G
Methods Mol Med
. 2011 Mar;
15:555-77.
PMID: 21390766
Aminoglycosides have been cinically used since 1944. Although this class of antibacterial agents has some nephrotoxicity and ototoxtcity issues, they continue to be part of the hospital armamentarium because of...
2.
Mann P, Xiong L, Mankin A, Chau A, Mendrick C, Najarian D, et al.
Mol Microbiol
. 2001 Oct;
41(6):1349-56.
PMID: 11580839
Enterococcus faecium strain 9631355 was isolated from animal sources on the basis of its resistance to the growth promotant avilamycin. The strain also exhibited high-level resistance to evernimicin, a drug...
3.
Hare R, Walker S, Dorman T, GREENE J, Guzman L, Kenney T, et al.
J Bacteriol
. 2001 Feb;
183(5):1694-706.
PMID: 11160101
In vivo genetic footprinting was developed in the yeast Saccharomyces cerevisiae to simultaneously assess the importance of thousands of genes for the fitness of the cell under any growth condition....
4.
Jones R, Hare R, Sabatelli F
J Antimicrob Chemother
. 2001 Jan;
47(1):15-25.
PMID: 11152427
The antimicrobial activity of evernimicin (formerly SCH 27899), a novel oligosaccharide antimicrobial of the everninomicin class, was evaluated against four groups of Gram-positive pathogens: (i) Streptococcus pneumoniae (n = 1452);...
5.
McNicholas P, Mann P, Najarian D, Miesel L, Hare R, Black T
Antimicrob Agents Chemother
. 2000 Dec;
45(1):79-83.
PMID: 11120948
Chemical mutagenesis of Staphylococcus aureus RN450 generated two strains that displayed a stable reduction (30- to 60-fold) in susceptibility to evernimicin. Cell-free translation reactions demonstrated that the resistance determinant was...
6.
Adrian P, Mendrick C, Loebenberg D, McNicholas P, Shaw K, Klugman K, et al.
Antimicrob Agents Chemother
. 2000 Oct;
44(11):3101-6.
PMID: 11036030
Spontaneous mutants of susceptible clinical and laboratory isolates of Streptococcus pneumoniae exhibiting reduced susceptibility to evernimicin (SCH27899; MIC, 0.5 to 4.0 mg/liter) were selected on plates containing evernimicin. Four isolates...
7.
Cacciapuoti A, Loebenberg D, Corcoran E, Menzel Jr F, Moss Jr E, Norris C, et al.
Antimicrob Agents Chemother
. 2000 Jul;
44(8):2017-22.
PMID: 10898669
SCH 56592 (posaconazole), a new triazole antifungal agent, was tested in vitro, and its activity was compared to that of itraconazole against 39 Aspergillus strains and to that of fluconazole...
8.
Brieland J, Loebenberg D, Menzel F, Hare R
Antimicrob Agents Chemother
. 2000 Apr;
44(5):1333-6.
PMID: 10770771
The efficacy of SCH27899, a new everninomicin antibiotic, against replicative Legionella pneumophila lung infections in an immunocompromised host was evaluated using a murine model of Legionnaires' disease. A/J mice were...
9.
McNicholas P, Najarian D, Mann P, Hesk D, Hare R, Shaw K, et al.
Antimicrob Agents Chemother
. 2000 Apr;
44(5):1121-6.
PMID: 10770739
Evernimicin (SCH 27899) is a new antibiotic with activity against a wide spectrum of gram-positive bacteria and activity against some gram-negative bacteria. Previous metabolic labeling studies indicated that evernimicin specifically...
10.
Adrian P, Zhao W, Black T, Shaw K, Hare R, Klugman K
Antimicrob Agents Chemother
. 2000 Feb;
44(3):732-8.
PMID: 10681347
A clinical isolate of Streptococcus pneumoniae (SP#5) that showed decreased susceptibility to evernimicin (MIC, 1.5 microgram/ml) was investigated. A 4,255-bp EcoRI fragment cloned from SP#5 was identified by its ability...