R S Conlan
Overview
Explore the profile of R S Conlan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
297
Followers
0
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Recent Articles
1.
Paravati R, De Mello N, Onyido E, Francis L, Brusehafer K, Younas K, et al.
J Mol Med (Berl)
. 2020 Oct;
98(12):1713-1725.
PMID: 33047155
Endometrial receptivity is mediated by adhesion molecules at the endometrium-trophoblast interface where osteopontin (OPN) and CD44 form a protein complex that plays an important role in embryo recognition. Here, we...
2.
Toubhans B, Gourlan A, Telouk P, Lutchman-Singh K, Francis L, Conlan R, et al.
J Trace Elem Med Biol
. 2020 Jul;
62:126611.
PMID: 32652467
Background: Ovarian cancer diagnosis is currently based on imaging and circulating CA-125 concentrations with well-known limits to sensitivity and specificity. New biomarkers are required to complement CA-125 testing to increase...
3.
Sawhney M, Conlan R
Biomed Microdevices
. 2019 Jul;
21(3):70.
PMID: 31273464
Point-of-care medical devices offer the potential for rapid biomarker detection and reporting of medical conditions, thereby bypassing the requirements for offline clinical laboratory facilities in many cases. Label-free electrochemical techniques...
4.
Teixeira S, Abreu C, Parkes L, Davies J, Yao S, Sawhney M, et al.
Biosens Bioelectron
. 2019 Jun;
141:111386.
PMID: 31220725
DNA methylation and histone deacetylation are key epigenetic processes involved in normal cellular function and tumorigenesis. Therapeutic strategies based on DNA methyltransferase (DNMT) and histone deacetylase (HDAC) inhibitors are currently...
5.
Bissardon C, Proux O, Bureau S, Suess E, Winkel L, Conlan R, et al.
Analyst
. 2019 Apr;
144(11):3488-3493.
PMID: 30939183
The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that...
6.
MacKintosh S, Serino L, Iddon P, Brown R, Conlan R, Wright C, et al.
Biofabrication
. 2015 May;
7(2):025010.
PMID: 26019144
Endometrial stromal and epithelial cell function is typically studied in vitro using standard two-dimensional monocultures, but these cultures fail to reflect the complex three-dimensional (3D) architecture of tissue. A 3D...
7.
Gonzalez D, Thackeray H, Lewis P, Mantani A, Brook N, Ahuja K, et al.
J Clin Endocrinol Metab
. 2012 Jan;
97(3):957-66.
PMID: 22238403
Context: In fertile patients the endometrial Wilms tumor suppressor gene (WT1) is expressed during the window of implantation. Polycystic ovary syndrome (PCOS) patients suffer from hyperandrogenemia and infertility and have...
8.
Khan I, Gonzalez L, Francis L, Conlan R, Gilbert S, Singhrao S, et al.
Eur Cell Mater
. 2011 Nov;
22:190-201.
PMID: 22042737
The failure of cartilages to fuse, particularly in the case of articular cartilage under conditions of repair is due to morphological and structural constraints of the tissue. Factors that impede...
9.
Francis L, Gonzalez D, Ryder T, Baer K, Rees M, White J, et al.
J Microsc
. 2010 Oct;
240(2):111-21.
PMID: 20946377
Atomic force microscopy enables the simultaneous acquisition of high-resolution topographical and biophysical data allowing integrated analysis of cell surfaces during development and pathogenesis, and, critically, can link molecular and biophysical...
10.
Margarit L, Taylor A, Roberts M, Hopkins L, Davies C, Brenton A, et al.
J Clin Endocrinol Metab
. 2010 Sep;
95(12):5320-9.
PMID: 20826587
Context: Endometrium of fertile women expresses progesterone-regulated Mucin 1 (MUC1) that carries selectin ligands recognized by the human blastocyst. Altered MUC1 expression at the time of implantation may contribute to...