» Authors » R Robert Vethanayagam

R Robert Vethanayagam

Explore the profile of R Robert Vethanayagam including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 544
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Yang S, Cai Q, Vethanayagam R, Wang J, Yang W, Hu B
Hear Res . 2015 Nov; 333:283-294. PMID: 26520584
Our previous RNA-sequencing analysis of the rat cochlear genes identified multiple biological processes and molecular pathways in the cochlear response to acoustic overstimulation. However, the biological processes and molecular pathways...
2.
Cai Q, Vethanayagam R, Yang S, Bard J, Jamison J, Cartwright D, et al.
J Neuroinflammation . 2014 Oct; 11:173. PMID: 25311735
Background: The cochlea is the sensory organ of hearing. In the cochlea, the organ of Corti houses sensory cells that are susceptible to pathological insults. While the organ of Corti...
3.
Godoy H, Khan A, Vethanayagam R, Grimm M, Singel K, Kolomeyevskaya N, et al.
PLoS One . 2013 Aug; 8(7):e69631. PMID: 23922763
The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived...
4.
Grimm M, Vethanayagam R, Almyroudis N, Dennis C, Khan A, DAuria A, et al.
J Immunol . 2013 Mar; 190(8):4175-84. PMID: 23509361
Chronic granulomatous disease, an inherited disorder of the NADPH oxidase in which phagocytes are defective in the generation of superoxide anion and downstream reactive oxidant species, is characterized by severe...
5.
Davidson B, Vethanayagam R, Grimm M, Mullan B, Raghavendran K, Blackwell T, et al.
J Immunol . 2013 Jan; 190(4):1714-24. PMID: 23296708
Recruitment of neutrophils and release of reactive oxygen species are considered to be major pathogenic components driving acute lung injury (ALI). However, NADPH oxidase, the major source of reactive oxygen...
6.
Montecinos V, Godoy A, Hinklin J, Vethanayagam R, Smith G
PLoS One . 2012 Feb; 7(1):e29623. PMID: 22303438
Characterization of the mechanism(s) of androgen-driven human angiogenesis could have significant implications for modeling new forms of anti-angiogenic therapies for CaP and for developing targeted adjuvant therapies to improve efficacy...
7.
Vethanayagam R, Almyroudis N, Grimm M, Lewandowski D, Pham C, Blackwell T, et al.
PLoS One . 2011 Dec; 6(12):e28149. PMID: 22163282
NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are...
8.
Lugade A, Vethanayagam R, Nasirikenari M, Bogner P, Segal B, Thanavala Y
Am J Respir Cell Mol Biol . 2011 Jan; 45(3):557-65. PMID: 21216970
Nrf2 is a leucine zipper transcription factor that protects against oxidant-induced injury. Nontypeable Haemophilus influenzae is responsible for frequent disease exacerbations in patients with chronic obstructive pulmonary disease and is...
9.
Godoy A, Montecinos V, Gray D, Sotomayor P, Yau J, Vethanayagam R, et al.
Am J Physiol Endocrinol Metab . 2010 Aug; 300(2):E263-75. PMID: 20699437
The response of the prostate tissue microenvironment to androgen deprivation (AD) represents a critical component in the treatment of benign prostatic hyperplasia and prostate cancer (CaP). Primary xenografts of human...
10.
Grimm M, Vethanayagam R, Almyroudis N, Lewandowski D, Rall N, Blackwell T, et al.
Med Mycol . 2010 Jun; 49 Suppl 1:S144-9. PMID: 20560866
NADPH oxidase plays a critical role in antimicrobial host defense, as evident in chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase characterized by severe bacterial and fungal...