R R Hardy
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Explore the profile of R R Hardy including associated specialties, affiliations and a list of published articles.
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118
Citations
6010
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Recent Articles
1.
Hayakawa K, Formica A, Colombo M, Shinton S, Brill-Dashoff J, Morse Iii H, et al.
Leukemia
. 2016 Apr;
30(7):1510-9.
PMID: 27055869
A common feature of B-cell chronic lymphocytic leukemia (CLL) is chromosomal loss of 13q14, containing the miR15a/16-1 locus controlling B-cell proliferation. However, CLL etiology remains unclear. CLL is an adult...
2.
Parks D, Hardy R, Herzenberg L
Immunol Today
. 2014 Oct;
4(5):145-50.
PMID: 25291674
Investigations of the nature and functions of the immune system and its cell populations have been revolutionized by the techniques of fluorescence-activated cell sorting (FA CS) and flow cytometry. Over...
3.
Allman D, Lindsley R, DEMUTH W, Rudd K, Shinton S, Hardy R
J Immunol
. 2001 Dec;
167(12):6834-40.
PMID: 11739500
Although immature/transitional peripheral B cells may remain susceptible to selection pressures before full maturation, the nature and timing of these selection events remain unclear. We show that correlated expression of...
4.
Gui M, Li J, Wen L, Hardy R, Hayakawa K
J Immunol
. 2001 Nov;
167(11):6239-46.
PMID: 11714786
CD1d-dependent accumulation of alphabeta T cells bearing a canonical Valpha14Jalpha281 alpha-chain (Valpha14+ T cells) is thought to model positive selection of lipid-specific T cells, based on their ability to recognize...
5.
Roederer M, Hardy R
Cytometry
. 2001 Oct;
45(1):56-64.
PMID: 11598947
Background: In multivariate distributions (for example, in 3- or more color flow cytometric datasets), it can become difficult or impossible to identify populations that differ between samples based only on...
6.
Roederer M, Moore W, Treister A, Hardy R, Herzenberg L
Cytometry
. 2001 Oct;
45(1):47-55.
PMID: 11598946
Background: While several algorithms for the comparison of univariate distributions arising from flow cytometric analyses have been developed and studied for many years, algorithms for comparing multivariate distributions remain elusive....
7.
Hardy R, Hayakawa K
Annu Rev Immunol
. 2001 Mar;
19:595-621.
PMID: 11244048
B cell development is a highly regulated process whereby functional peripheral subsets are produced from hematopoietic stem cells, in the fetal liver before birth and in the bone marrow afterward....
8.
Hardy R, Wasserman R, Li Y, Shinton S, Hayakawa K
Curr Top Microbiol Immunol
. 2000 Dec;
252:25-30.
PMID: 11125482
The expression of different sets of immunoglobulin specificities by fetal and adult B lymphocytes is a longstanding puzzle in immunology. In the past few years it has become clear that...
9.
Hayakawa K, Shinton S, Asano M, Hardy R
Curr Top Microbiol Immunol
. 2000 Dec;
252:15-22.
PMID: 11125472
No abstract available.
10.
Hardy R, Li Y, Allman D, Asano M, Gui M, Hayakawa K
Immunol Rev
. 2000 Aug;
175:23-32.
PMID: 10933588
Here we review three areas in B-cell development in the mouse, with a focus on relevance to B-1/CD5+ B cells. Multiparameter flow cytometry has allowed the dissection of intermediate stages...