R Paul Wilson
Overview
Explore the profile of R Paul Wilson including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
2063
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0
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Recent Articles
1.
Inan S, Wilson R, Tukel C
Pharmacol Res
. 2025 Mar;
:107693.
PMID: 40086611
Gut microbial dysbiosis, or altered gut microbial communities, in Alzheimer's Disease suggests a pathogenic role for gut inflammation and microbial products in shaping a neuroinflammatory environment. Similarly, metabolic diseases, such...
2.
Miller A, Pasternak J, Medeiros N, Nicastro L, Tursi S, Hansen E, et al.
PLoS Pathog
. 2020 Jul;
16(7):e1008591.
PMID: 32645118
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory responses...
3.
Wilson R, McGettigan S, Dang V, Kumar A, Cancro M, Nikbakht N, et al.
J Invest Dermatol
. 2019 Jun;
139(12):2477-2487.
PMID: 31152755
Antibodies are key to cutaneous host defense and inflammation. Despite their importance, the mechanisms by which skin antibodies are sustained are poorly described. Here, we identified that, in addition to...
4.
Wilson R, Tursi S, Rapsinski G, Medeiros N, Le L, Kotredes K, et al.
PLoS Pathog
. 2019 Apr;
15(4):e1007745.
PMID: 31009517
The mechanisms by which the gut luminal environment is disturbed by the immune system to foster pathogenic bacterial growth and survival remain incompletely understood. Here, we show that STAT2 dependent...
5.
Biesecker S, Nicastro L, Wilson R, Tukel C
Biomolecules
. 2018 Jan;
8(1).
PMID: 29364839
strains may be beneficial or pathogenic. Many strains that cause human disease, especially those responsible for bacteremia and sepsis, express virulence factors that impart resistance to the complement system. The...
6.
Zhu W, Winter M, Byndloss M, Spiga L, Duerkop B, Hughes E, et al.
Nature
. 2018 Jan;
553(7687):208-211.
PMID: 29323293
Inflammatory diseases of the gastrointestinal tract are frequently associated with dysbiosis, characterized by changes in gut microbial communities that include an expansion of facultative anaerobic bacteria of the Enterobacteriaceae family...
7.
Oppong G, Rapsinski G, Tursi S, Biesecker S, Klein-Szanto A, Goulian M, et al.
NPJ Biofilms Microbiomes
. 2016 Feb;
1.
PMID: 26855788
Background/objectives: A disruption of epithelial barrier function can lead to intestinal inflammation. Toll-like receptor (TLR) 2 activation by microbial products promotes intestinal epithelial integrity and overall gut health. Several bacterial...
8.
Gallo P, Rapsinski G, Wilson R, Oppong G, Sriram U, Goulian M, et al.
Immunity
. 2015 Jun;
42(6):1171-84.
PMID: 26084027
Research on the human microbiome has established that commensal and pathogenic bacteria can influence obesity, cancer, and autoimmunity through mechanisms mostly unknown. We found that a component of bacterial biofilms,...
9.
Rapsinski G, Wynosky-Dolfi M, Oppong G, Tursi S, Wilson R, Brodsky I, et al.
Infect Immun
. 2014 Nov;
83(2):693-701.
PMID: 25422268
Amyloids are proteins with cross-β-sheet structure that contribute to pathology and inflammation in complex human diseases, including Alzheimer's disease, Parkinson's disease, type II diabetes, and secondary amyloidosis. Bacteria also produce...
10.
Wangdi T, Lee C, Spees A, Yu C, Kingsbury D, Winter S, et al.
PLoS Pathog
. 2014 Aug;
10(8):e1004306.
PMID: 25101794
Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a disseminated infection, while the closely related pathogen S. enterica serovar Typhimurium (S. Typhimurium) is associated with a localized gastroenteritis in...