Cagla Tukel
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Explore the profile of Cagla Tukel including associated specialties, affiliations and a list of published articles.
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51
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1737
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Recent Articles
1.
Inan S, Wilson R, Tukel C
Pharmacol Res
. 2025 Mar;
:107693.
PMID: 40086611
Gut microbial dysbiosis, or altered gut microbial communities, in Alzheimer's Disease suggests a pathogenic role for gut inflammation and microbial products in shaping a neuroinflammatory environment. Similarly, metabolic diseases, such...
2.
Cimini M, Hansmann U, Gonzalez C, Chesney A, Truongcao M, Gao E, et al.
Cell Rep
. 2025 Mar;
44(3):115408.
PMID: 40056419
Cardiac amyloidosis is a secondary phenomenon of an already pre-existing chronic condition. Whether cardiac amyloidosis represents one of the complications post myocardial infarction (MI) has yet to be fully understood....
3.
Taddeo J, Wilson N, Kowal A, Beld J, Andres K, Tukel C, et al.
Gut Microbes
. 2024 Nov;
16(1):2419567.
PMID: 39508622
Typhimurium (STm) is a causative pathogen for robust inflammatory gastrointestinal disease and can lead to systemic infection. Eicosanoids, bioactive lipid mediators, play a crucial role in modulating both the induction...
4.
Grando K, Bessho S, Harrell K, Kyrylchuk K, Pantoja A, Olubajo S, et al.
Gut Microbes
. 2024 Aug;
16(1):2392877.
PMID: 39189642
serovar Typhimurium (STm) causes gastroenteritis and can progress to reactive arthritis (ReA). STm forms biofilms in the gut that secrete the amyloid curli, which we previously demonstrated can trigger autoimmunity...
5.
Albicoro F, Bessho S, Grando K, Olubajo S, Tam V, Tukel C
Infect Immun
. 2024 Aug;
92(10):e0026624.
PMID: 39133016
serovar Typhimurium (. Typhimurium) infection triggers an inflammatory response that changes the concentration of metabolites in the gut impacting the luminal environment. Some of these environmental adjustments are conducive to...
6.
Cimini M, Hansmann U, Gonzalez C, Chesney A, Truongcao M, Gao E, et al.
bioRxiv
. 2024 Jul;
PMID: 39005419
Background: Amyloidosis is a major long-term complication of chronic disease; however, whether it represents one of the complications of post-myocardial infarction (MI) is yet to be fully understood. Methods: Using...
7.
Elkins M, Jain N, Tukel C
Curr Opin Microbiol
. 2024 Apr;
79:102473.
PMID: 38608623
Bacteria are known to produce amyloids, proteins characterized by a conserved cross-beta sheet structure, which exhibit structural and functional similarities to human amyloids. The deposition of human amyloids into fibrillar...
8.
Verstraelen P, Van Remoortel S, De Loose N, Verboven R, Garcia-Diaz Barriga G, Christmann A, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Mar;
18(1):89-104.
PMID: 38556049
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown. Given its potential relevance for...
9.
Inan S, Meissler J, Bessho S, Wiah S, Tukel C, Eisenstein T, et al.
Brain Behav Immun
. 2024 Jan;
117:100-111.
PMID: 38199516
Oxycodone is the most prescribed opioid for pain management and has been available in clinics for almost a century, but effects of chronic oxycodone have been studied less than morphine...
10.
Bessho S, Grando K, Kyrylchuk K, Miller A, Klein-Szanto A, Zhu W, et al.
Gut Microbes
. 2023 Jun;
15(1):2221813.
PMID: 37317012
The biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following infection. Systemic curli injections or infection of mice with Typhimurium induce the major features...