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R Paul Symonds

Explore the profile of R Paul Symonds including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 361
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Recent Articles
1.
Jaikuna T, Wilson F, Azria D, Chang-Claude J, De Santis M, Gutierrez-Enriquez S, et al.
Phys Imaging Radiat Oncol . 2024 Sep; 32:100635. PMID: 39310222
Background And Purpose: Image-based data mining (IBDM) requires spatial normalisation to reference anatomy, which is challenging in breast radiotherapy due to variations in the treatment position, breast shape and volume....
2.
Naderi E, Aguado-Barrera M, Schack L, Dorling L, Rattay T, Fachal L, et al.
JNCI Cancer Spectr . 2023 Oct; 7(6). PMID: 37862240
Background: This study was designed to identify common genetic susceptibility and shared genetic variants associated with acute radiation-induced toxicity across 4 cancer types (prostate, head and neck, breast, and lung)....
3.
Jaikuna T, Vasquez Osorio E, Azria D, Chang-Claude J, De Santis M, Gutierrez-Enriquez S, et al.
Breast . 2023 Sep; 72:103578. PMID: 37713940
Background: Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conserving surgery (BCS) and radiotherapy (RT) to the breast. However, they are subject...
4.
Jandu H, Veal C, Fachal L, Luccarini C, Aguado-Barrera M, Altabas M, et al.
Radiother Oncol . 2023 Jul; 187:109806. PMID: 37437607
Background And Purpose: Up to a quarter of breast cancer patients treated by surgery and radiotherapy experience clinically significant toxicity. If patients at high risk of adverse effects could be...
5.
Heumann P, Aguado-Barrera M, Avuzzi B, Azria D, Briers E, Bultijnck R, et al.
Radiother Oncol . 2022 Nov; 178:109426. PMID: 36442608
Introduction: Previous studies showed that healthcare professionals and patients had only moderate to low agreement on their assessment of treatment-related symptoms. We aimed to determine the levels of agreement in...
6.
Webb A, Harper E, Rattay T, Aguado-Barrera M, Azria D, Bourgier C, et al.
EBioMedicine . 2022 Sep; 84:104269. PMID: 36130474
Background: Circadian rhythm impacts broad biological processes, including response to cancer treatment. Evidence conflicts on whether treatment time affects risk of radiotherapy side-effects, likely because of differing time analyses and...
7.
Aldraimli M, Osman S, Grishchuck D, Ingram S, Lyon R, Mistry A, et al.
Adv Radiat Oncol . 2022 Jun; 7(3):100890. PMID: 35647396
Purpose: Some patients with breast cancer treated by surgery and radiation therapy experience clinically significant toxicity, which may adversely affect cosmesis and quality of life. There is a paucity of...
8.
Kerns S, Amidon Morlang A, Lee S, Peterson D, Marples B, Zhang H, et al.
Radiother Oncol . 2022 Jan; 168:75-82. PMID: 35077710
Background And Purpose: Genome-wide association studies (GWAS) of late hematuria following prostate cancer radiotherapy identified single nucleotide polymorphisms (SNPs) near AGT, encoding angiotensinogen. We tested the hypothesis that patients taking...
9.
Aldraimli M, Soria D, Grishchuck D, Ingram S, Lyon R, Mistry A, et al.
Comput Biol Med . 2021 Jul; 135:104624. PMID: 34247131
The prediction by classification of side effects incidence in a given medical treatment is a common challenge in medical research. Machine Learning (ML) methods are widely used in the areas...
10.
Rattay T, Seibold P, Aguado-Barrera M, Altabas M, Azria D, Barnett G, et al.
Front Oncol . 2020 Nov; 10:575909. PMID: 33216838
Acute skin toxicity is a common and usually transient side-effect of breast radiotherapy although, if sufficiently severe, it can affect breast cosmesis, aftercare costs and the patient's quality-of-life. The aim...