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Dirk De Ruysscher

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Articles 379
Citations 8586
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Recent Articles
1.
Farazi M, Yang X, Gehl C, Barnett G, Burnet N, Chang-Claude J, et al.
Cancer Epidemiol Biomarkers Prev . 2025 Mar; PMID: 40029246
Background: Late bladder toxicity is a concern for patients receiving prostate cancer radiotherapy and negatively impacts survivors. Few risk factors are known beyond the radiation dose and volume of bladder...
2.
Garrett Fernandes M, Bussink J, Wijsman R, Gouw Z, Weiss A, Sijtsema N, et al.
Radiother Oncol . 2025 Feb; 206:110821. PMID: 39993599
Background And Purpose: Inconsistencies in identifying dose-limiting cardiovascular substructures for treating stage III non-small cell lung cancer (NSCLC) have hindered the implementation of cardiac sparing treatment planning guidelines. This study...
3.
Cortiula F, Kutiel T, Hsu M, Hendriks L, Nassar A, Moskovitz M, et al.
Eur J Cancer . 2025 Feb; 219:115302. PMID: 39987799
Introduction: The current standard of care for fit patients with unresectable stage III NSCLC involves concurrent chemoradiation (CRT) followed by durvalumab. Disease recurrence occurs in approximately 2/3 of patients, often...
4.
Hattu D, Emans D, Bouten J, Canters R, van Loon J, De Ruysscher D
Phys Imaging Radiat Oncol . 2025 Feb; 33:100699. PMID: 39935553
Background And Purpose: In non-small cell lung cancer (NSCLC) a significant portion of the planning target volume (PTV) margin accommodates for anatomical changes during treatment. Patients with no or minimal...
5.
Bouzaki A, Green D, Van Herk M, Shortall J, Puri T, Kerns S, et al.
Phys Imaging Radiat Oncol . 2025 Feb; 33:100701. PMID: 39927213
Background And Purpose: Growing evidence suggests that spatial dose variations across the rectal surface influence toxicity risk after radiotherapy. Existing methodologies employ a fixed, arbitrary physical extent for rectal dose...
6.
Zhang X, Peeters S, Huysmans S, Houben R, Marcuse F, Hochstenbag M, et al.
Eur J Surg Oncol . 2025 Feb; 51(5):109639. PMID: 39892088
Introduction: Pleural metastases are common in thymic epithelial tumors (TET), which include pleural recurrence and stage IVa at initial diagnosis. However, the specific risk factors predicting its recurrence (i.e., pleural...
7.
Yan M, Zhang Z, Tian J, Yu J, Dekker A, De Ruysscher D, et al.
Radiat Oncol . 2025 Jan; 20(1):9. PMID: 39825409
Background: Several studies have suggested that lung tissue heterogeneity is associated with overall survival (OS) in lung cancer. However, the quantitative relationship between the two remains unknown. The purpose of...
8.
Taasti V, Kneepkens E, van der Stoep J, Velders M, Cobben M, Vullings A, et al.
Phys Med . 2025 Jan; 130:104890. PMID: 39799813
Purpose: Proton therapy of moving targets is considered a challenge. At Maastro, we started treating lung cancer patients with proton therapy in October 2019. In this work, we summarise the...
9.
McWilliam A, Marshall D, Kerns S, Barnett G, Vega A, Kapouranis T, et al.
J Natl Cancer Inst . 2025 Jan; PMID: 39761002
Purpose: Overlapping genes are involved with rheumatoid arthritis (RA) and DNA repair pathways. Therefore, we hypothesised that patients with a high polygenic risk score (PRS) for RA will have an...
10.
Aguado-Barrera M, Lopez-Pleguezuelos C, Gomez-Caamano A, Calvo-Crespo P, Taboada-Valladares B, Azria D, et al.
Lung Cancer . 2024 Dec; 199:108072. PMID: 39740425
Background And Purpose: We investigate discrepancies in the assessment of treatment-related symptoms in lung cancer between healthcare professionals and patients, and factors contributing to these discrepancies. Materials And Methods: Data...