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R P Rubin

Explore the profile of R P Rubin including associated specialties, affiliations and a list of published articles. Areas
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Articles 107
Citations 1341
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Lee B, Sessanna S, Laychock S, Rubin R
J Membr Biol . 2002 Oct; 189(3):181-90. PMID: 12395283
Functional and molecular biological evidence exists for the expression of ryanodine receptors in non-muscle cells. In the present study, RT-PCR and 5'-rapid amplification of cDNA 5'-end (5'-RACE analysis) provided evidence...
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Zhang X, Wen J, Bidasee K, Besch Jr H, Wojcikiewicz R, Lee B, et al.
Biochem J . 1999 May; 340 ( Pt 2):519-27. PMID: 10333498
The present study examines the cellular distribution of the ryanodine receptor/channel (RyR) and inositol 1,4,5-trisphosphate receptor (InsP3R) subtypes in parotid acini. Using fluorescently labelled 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-3-propionic acid glycyl-ryanodine (BODIPYtrade mark-ryanodine) and...
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Zhu Y, Aletta J, Wen J, Zhang X, Higgins D, Rubin R
Am J Physiol . 1998 Aug; 275(2):G259-68. PMID: 9688653
To establish a continuous cell line, freshly prepared rat parotid acinar cells were stably transfected with a plasmid vector containing the SV40 large T antigen. The acinar origin of these...
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Zhang X, Wen J, Bidasee K, Besch Jr H, Rubin R
Am J Physiol . 1997 Nov; 273(4):C1306-14. PMID: 9357775
The ryanodine receptor mediates intracellular Ca2+ mobilization in muscle and nerve, but its physiological role in nonexcitable cells is less well defined. Like adenosine 3',5'-cyclic monophosphate and inositol 1,4,5-trisphosphate, cyclic...
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Zhang X, Wen J, Aletta J, Rubin R
Exp Cell Res . 1997 May; 233(1):225-31. PMID: 9184091
AR4-2J pancreatoma cells were stably transfected with an expression vector containing the cDNA for PKC-alpha in the antisense orientation. Transfectants designated antisense-alpha AA1, AA2, and AA3 exhibited marked reductions in...
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Terzian A, Zhang X, Rubin R
Biochem Pharmacol . 1996 Aug; 52(4):569-77. PMID: 8759029
We investigated the expression, distribution, and activation parameters of protein kinase C (PKC) isozymes in isolated rat parotid acinar cells. By analyzing cellular extracts by western blot analysis and for...
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Koshlukova S, Rubin R, Withiam-Leitch M, Aletta J
Cell Signal . 1995 Aug; 7(6):559-69. PMID: 8588972
Epidermal growth factor (EGF) stimulates secretion of glycoprotein 2 (GP2) in a time-and concentration-dependent manner from the AR4-2J pancreatoma cell line. Cell differentiation induced by dexamethasone treatment for 3 d,...
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Withiam-Leitch M, Rubin R, Koshlukova S, Aletta J
J Biol Chem . 1995 Feb; 270(8):3780-7. PMID: 7876119
Salt-washed (0.6 m NaCl) zymogen granule membranes (ZGM) of rat pancreatic acinar cells were utilized to identify and characterize membrane protein(s) responsible for phospholipase and lysophospholipase activities. Five major bands...
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Rubin R, Adolf M
J Pharmacol Exp Ther . 1994 Feb; 268(2):600-6. PMID: 7509390
This study examined the mechanistic basis of the synergistic interaction between the cyclic AMP (cAMP) and phosphoinositide pathways in salivary amylase secretion. cAMP produced a concentration-dependent increase in Ca++ mobilization...