R P Narsimhan
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Explore the profile of R P Narsimhan including associated specialties, affiliations and a list of published articles.
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15
Citations
870
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Recent Articles
1.
Auger K, Wang J, Narsimhan R, Holcombe T, Roberts T
Biochem Biophys Res Commun
. 2000 Jun;
272(3):822-9.
PMID: 10860837
The discovery that the PTEN tumor suppressor encodes a phosphoinositide 3-phosphatase has raised interest in the effects of constitutive activation of PI 3-kinase. To gain insight into PI 3-kinase function,...
2.
Xia K, Lee R, Narsimhan R, Mukhopadhyay N, Neel B, Roberts T
Mol Cell Biol
. 1999 Jun;
19(7):4819-24.
PMID: 10373531
There is a growing body of evidence demonstrating that Raf-1 is phosphorylated on tyrosines upon stimulation of a variety of receptors. Although detection of Raf-1 tyrosine phosphorylation has remained elusive,...
3.
Raptis L, Brownell H, Lu Y, Preston T, Narsimhan R, Anderson S, et al.
Exp Cell Res
. 1997 Aug;
235(1):188-97.
PMID: 9281368
To investigate the functional relationship between the transforming ability of Ras and its role as an integral component of the differentiative insulin signaling pathway, we introduced a leu61-activated ras gene...
4.
Raptis L, Yang J, Brownell H, Lai J, Preston T, Corbley M, et al.
Cell Growth Differ
. 1997 Jan;
8(1):11-21.
PMID: 8993830
To investigate the functional relationship between the transforming ability of Ras and its role as an integral component of the differentiation-promoting insulin signaling pathway, we introduced a leu61-activated ras gene...
5.
Xia K, Mukhopadhyay N, Inhorn R, Barber D, Rose P, Lee R, et al.
Proc Natl Acad Sci U S A
. 1996 Oct;
93(21):11681-6.
PMID: 8876196
JAK2, a member of the Janus kinase superfamily was found to interact functionally with Raf-1, a central component of the ras/mitogen-activated protein kinase signal transduction pathway. Interferon-gamma and several other...
6.
Brownell H, Narsimhan R, Corbley M, Mann V, Whitfield J, Raptis L
DNA Cell Biol
. 1996 Jun;
15(6):443-51.
PMID: 8672240
A decrease in gap junctional, intercellular communication (GJIC) has been associated with cells neoplastically transformed by a variety of factors. To investigate the role of the Ras oncogene product in...
7.
Salmeron A, Ahmad T, Carlile G, Pappin D, Narsimhan R, Ley S
EMBO J
. 1996 Feb;
15(4):817-26.
PMID: 8631303
The Tpl-2 protein serine/threonine kinase was originally identified, in a C-terminally deleted form, as the product of an oncogene associated with the progression of Moloney murine leukemia virus-induced T cell...
8.
Fu H, Xia K, Pallas D, Cui C, Conroy K, Narsimhan R, et al.
Science
. 1994 Oct;
266(5182):126-9.
PMID: 7939632
Members of a family of highly conserved proteins, termed 14-3-3 proteins, were found by several experimental approaches to associate with Raf-1, a central component of a key signal transduction pathway....
9.
Saccone S, Narsimhan R, Gaudino G, Dalpra L, Comoglio P, Della Valle G
Genomics
. 1992 Jul;
13(3):912-4.
PMID: 1386343
No abstract available.
10.
Di Renzo M, Narsimhan R, Olivero M, Bretti S, Giordano S, Medico E, et al.
Oncogene
. 1991 Nov;
6(11):1997-2003.
PMID: 1719465
The MET oncogene encodes a transmembrane tyrosine kinase receptor. Recently, hepatocyte growth factor (HGF), a potent growth factor for hepatocytes involved in liver regeneration, has been proposed as a ligand....