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R Onrust

Explore the profile of R Onrust including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 854
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Recent Articles
1.
Lasham A, Lindridge E, Rudert F, Onrust R, Watson J
Gene . 2000 Jul; 252(1-2):1-13. PMID: 10903433
Fas (CD95/Apo-1) gene expression is dysregulated in a number of diseased states. Towards understanding the regulation of fas gene expression, we previously identified activator and repressor elements within the human...
2.
Guenther B, Onrust R, Sali A, ODonnell M, Kuriyan J
Cell . 1997 Nov; 91(3):335-45. PMID: 9363942
The crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III has been determined. Three consecutive domains in the structure are arranged in a...
3.
Onrust R, Herzmark P, Chi P, Garcia P, Lichtarge O, Kingsley C, et al.
Science . 1997 Jan; 275(5298):381-4. PMID: 8994033
Transmembrane receptors for hormones, neurotransmitters, light, and odorants mediate their cellular effects by activating heterotrimeric guanine nucleotide-binding proteins (G proteins). Crystal structures have revealed contact surfaces between G protein subunits,...
4.
Garcia P, Onrust R, Bell S, Sakmar T, Bourne H
EMBO J . 1995 Sep; 14(18):4460-9. PMID: 7556089
We have measured the activation by recombinant rhodopsin of the alpha-subunit (alpha 1) of retinal transducin (Gt, also recombinant) using a new assay. Cultured cells are transiently transfected with DNAs...
5.
Onrust R, Finkelstein J, Turner J, Naktinis V, ODonnell M
J Biol Chem . 1995 Jun; 270(22):13366-77. PMID: 7768938
The nine-subunit DNA polymerase (Pol) III* coupled to its beta sliding clamp is a rapid and highly processive replicating machine. The multiple subunits are needed for the complicated task of...
6.
Naktinis V, Onrust R, Fang L, ODonnell M
J Biol Chem . 1995 Jun; 270(22):13358-65. PMID: 7768937
The Escherichia coli replicase, DNA polymerase III holoenzyme, derives its processivity from the beta subunit sliding clamp that encircles DNA and tethers the replicase to the template. The beta dimer...
7.
Onrust R, Finkelstein J, Naktinis V, Turner J, Fang L, ODonnell M
J Biol Chem . 1995 Jun; 270(22):13348-57. PMID: 7768936
The gamma complex of DNA polymerase III holoenzyme, the replicase of Escherichia coli, couples ATP hydrolysis to the loading of beta sliding clamps onto primed DNA. The beta sliding clamp...
8.
Markby D, Onrust R, Bourne H
Science . 1993 Dec; 262(5141):1895-901. PMID: 8266082
Most members of the guanosine triphosphatase (GTPase) superfamily hydrolyze guanosine triphosphate (GTP) quite slowly unless stimulated by a GTPase activating protein or GAP. The alpha subunits (G alpha) of the...
9.
Blinkova A, Hervas C, Stukenberg P, Onrust R, ODonnell M, Walker J
J Bacteriol . 1993 Sep; 175(18):6018-27. PMID: 8376347
The replicative polymerase of Escherichia coli, DNA polymerase III, consists of a three-subunit core polymerase plus seven accessory subunits. Of these seven, tau and gamma are products of one replication...
10.
Onrust R, ODonnell M
J Biol Chem . 1993 Jun; 268(16):11766-72. PMID: 8505304
The gamma complex subassembly (gamma delta delta' chi psi) of DNA polymerase III holoenzyme couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. This...