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R O RECKNAGEL

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Articles 78
Citations 1265
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Recent Articles
1.
Glende Jr E, RECKNAGEL R
Toxicol Appl Pharmacol . 1992 Mar; 113(1):159-62. PMID: 1553751
It was found that the four toxigenic agents, CCl4, CHCl3, CBrCl3, and 1,1-dichloroethylene (vinylidene chloride) all share the property of activating phospholipase A2 (PLA2) of isolated hepatocytes in suspension, as...
2.
Glende Jr E, RECKNAGEL R
Res Commun Chem Pathol Pharmacol . 1991 Jul; 73(1):41-52. PMID: 1882126
The capacity of CCl4 to activate phospholipase A2 (PLA2) of isolated hepatocytes in suspension, and the toxicity of CCl4 against such hepatocytes, was confirmed. It was shown that these actions...
3.
Britton R, Ferrali M, Magiera C, RECKNAGEL R, Bacon B
Hepatology . 1990 Jun; 11(6):1038-43. PMID: 2365281
In the iron-loaded liver there may be an increase in the putative intracellular transit pool of iron, components of which could be catalytically active in stimulating lipid peroxidation. To study...
4.
RECKNAGEL R, Glende Jr E, Dolak J, Waller R
Pharmacol Ther . 1989 Jan; 43(1):139-54. PMID: 2675128
No abstract available.
5.
Dolak J, Waller R, Glende Jr E, RECKNAGEL R
J Biochem Toxicol . 1988 Jan; 3:329-42. PMID: 3236338
The calcium fluorescent probe fura2 was used to measure concentration of free calcium in the cytosol of isolated rat hepatocytes in suspension. The resting level in untreated hepatocytes was 121...
6.
Britton R, Bacon B, RECKNAGEL R
Chem Phys Lipids . 1987 Nov; 45(2-4):207-39. PMID: 3319227
Iron overload can have serious health consequences. Since humans lack an effective means to excrete excess iron, overload can result from an increased absorption of dietary iron or from parenteral...
7.
Dolak J, Britton R, Glende Jr E, RECKNAGEL R
J Biochem Toxicol . 1987 Jan; 2:57-66. PMID: 2469795
The effect of chlordecone (CD) on hepatic repair, measured either as recovery of microsomal enzymatic functions or as the induction of cytosolic thymidine kinase (TK) activity, was evaluated in rats...
8.
Britton R, Dolak J, Glende Jr E, RECKNAGEL R
J Biochem Toxicol . 1987 Jan; 2:43-55. PMID: 2469794
Chlordecone greatly potentiates carbon tetrachloride (CCl4) hepatotoxicity. In order to quantitate the degree of this potentiation, the effects of a range of doses of CCl4 on two microsomal enzymatic functions...
9.
Hegarty J, Glende Jr E, RECKNAGEL R
J Biochem Toxicol . 1986 Jun; 1(2):73-8. PMID: 2482892
The effect of carbon tetrachloride (CCl4) on the capacity of hepatic microsomes to sequester calcium was studied following pretreatment of rats with chlordecone. Chlordecone pretreatment alone had no effect on...
10.
Brattin W, Glende Jr E, RECKNAGEL R
J Free Radic Biol Med . 1985 Jan; 1(1):27-38. PMID: 3915301
Liver cell injury induced by carbon tetrachloride involves initially the metabolism of carbon tetrachloride to trichloromethyl free-radical by the mixed function oxidase system of the endoplasmic reticulum. It is postulated...