R Mackinnon
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Explore the profile of R Mackinnon including associated specialties, affiliations and a list of published articles.
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72
Citations
9061
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Recent Articles
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Mackinnon R, Wheeler K, Sokol J
J Perinatol
. 2011 Nov;
31(12):799-801.
PMID: 22124516
Management of atelectasis and lung collapse in ventilated neonates remains a common challenge in the neonatal intensive care unit. Recombinant human DNase (rhDNase) is an established treatment of atelectasis in...
3.
Hanison J, Jackson M, Mackinnon R
Br J Anaesth
. 2011 Feb;
106(3):422.
PMID: 21317238
No abstract available.
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Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution
Zhou Y, Kaufman A, Mackinnon R
Nature
. 2001 Nov;
414(6859):43-8.
PMID: 11689936
Ion transport proteins must remove an ion's hydration shell to coordinate the ion selectively on the basis of its size and charge. To discover how the K+ channel solves this...
7.
Zhou Y, Mackinnon R
Nature
. 2001 Nov;
414(6859):37-42.
PMID: 11689935
The K+ selectivity filter catalyses the dehydration, transfer and rehydration of a K+ ion in about ten nanoseconds. This physical process is central to the production of electrical signals in...
8.
Zhou M, Mann S, Mackinnon R
Nature
. 2001 Jun;
411(6838):657-61.
PMID: 11395760
Many voltage-dependent K+ channels open when the membrane is depolarized and then rapidly close by a process called inactivation. Neurons use inactivating K+ channels to modulate their firing frequency. In...
9.
Jiang Y, Pico A, Cadene M, Chait B, Mackinnon R
Neuron
. 2001 Apr;
29(3):593-601.
PMID: 11301020
The intracellular C-terminal domain structure of a six-transmembrane K+ channel from Escherichia coli has been solved by X-ray crystallography at 2.4 A resolution. The structure is representative of a broad...
10.
Marshall R, Spitzer R, Vaughan S, Vaughan R, Mellman L, Mackinnon R, et al.
Am J Psychiatry
. 2001 Feb;
158(2):319-21.
PMID: 11156821
Objective: To address both clinical and ethical concerns in psychiatric research, the study assessed the subjective experience of being a participant in a feasibility study of outcome in long-term psychodynamic...