R M Umek
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Explore the profile of R M Umek including associated specialties, affiliations and a list of published articles.
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19
Citations
1076
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Recent Articles
11.
Natale D, Umek R, Kowalski D
Nucleic Acids Res
. 1993 Feb;
21(3):555-60.
PMID: 8441667
Autonomously replicating sequence (ARS) elements function as plasmid replication origins. Our studies of the H4 ARS and ARS307 have established the requirement for a DNA unwinding element (DUE), a broad...
12.
Umek R
New Biol
. 1992 Mar;
4(3):203-6.
PMID: 1349820
The study of the mechanisms of transcriptional control continues to be an exciting area of research. The characterization of the constituents of the initiation complex and their interactions are leading...
13.
Cao Z, Umek R, McKnight S
Genes Dev
. 1991 Sep;
5(9):1538-52.
PMID: 1840554
In an effort to identify protein factors that play a regulatory role in the differentiation of adipocytes, we have isolated two genes that encode polypeptides related to CCAAT/enhancer-binding protein (C/EBP;...
14.
Umek R, Friedman A, McKnight S
Science
. 1991 Jan;
251(4991):288-92.
PMID: 1987644
The CCAAT-enhancer binding protein (C/EBP) has now been found to promote the terminal differentiation of adipocytes. During the normal course of adipogenesis, C/EBP expression is restricted to a terminal phase...
15.
Umek R, Kowalski D
Nucleic Acids Res
. 1990 Nov;
18(22):6601-5.
PMID: 2174542
We have previously identified a DNA unwinding element (DUE) in autonomously replicating sequences (ARSs) and demonstrated a correlation between single-strand-specific nuclease hypersensitivity of the DUE and ARS-mediated plasmid replication in...
16.
Umek R, Kowalski D
Proc Natl Acad Sci U S A
. 1990 Apr;
87(7):2486-90.
PMID: 2181439
Yeast replication origins contain a DNA sequence element whose biological activity correlates with hypersensitivity to single-strand-specific nucleases in negatively supercoiled plasmids. By using two-dimensional gel electrophoresis of plasmid topoisomers, we...
17.
Umek R, Linskens M, Kowalski D, Huberman J
Biochim Biophys Acta
. 1989 Jan;
1007(1):1-14.
PMID: 2642383
No abstract available.
18.
Umek R, Kowalski D
Cell
. 1988 Feb;
52(4):559-67.
PMID: 2830028
We have localized the DNA sequence that facilitates unwinding of a yeast replication origin, the H4 ARS. The readily unwound sequence lies adjacent to the previously characterized consensus core sequence...
19.
Umek R, Kowalski D
Nucleic Acids Res
. 1987 Jun;
15(11):4467-80.
PMID: 3035495
Mung bean nuclease was used to probe for DNA unwinding in torsionally-stressed chimeric plasmids containing two micron plasmid sequences and the yeast LEU2 gene in a pBR322 vector. The yeast...