R M Snider
Overview
Explore the profile of R M Snider including associated specialties, affiliations and a list of published articles.
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56
Citations
701
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Recent Articles
1.
Horuk R, Shurey S, Ng H, May K, Bauman J, Islam I, et al.
Immunol Lett
. 2001 Apr;
76(3):193-201.
PMID: 11306147
The classic signs of acute cellular rejection during organ transplantation include the infiltration of mononuclear cells into the interstitium. This recruitment of leukocytes into the transplanted tissue is promoted by...
2.
Horuk R, Clayberger C, Krensky A, Wang Z, Grone H, Weber C, et al.
J Biol Chem
. 2000 Oct;
276(6):4199-204.
PMID: 11054419
Chemokines like RANTES appear to play a role in organ transplant rejection. Because RANTES is a potent agonist for the chemokine receptor CCR1, we examined whether the CCR1 receptor antagonist...
3.
Liang M, Mallari C, Rosser M, Ng H, May K, Monahan S, et al.
J Biol Chem
. 2000 Apr;
275(25):19000-8.
PMID: 10748002
The CC chemokine receptor-1 (CCR1) is a prime therapeutic target for treating autoimmune diseases. Through high capacity screening followed by chemical optimization, we identified a novel non-peptide CCR1 antagonist, R-N-[5-chloro-2-[2-[4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl...
4.
Liang M, Rosser M, Ng H, May K, Bauman J, Islam I, et al.
Eur J Pharmacol
. 2000 Feb;
389(1):41-9.
PMID: 10686294
The species specificity of a small molecule antagonist for the human CCR1 chemokine receptor, 2-2-diphenyl-5-(4-chlorophenyl)piperidin-1-yl)valeronitrile (CCR1 antagonist 1), has been examined using cloned CCR1 receptors from various species. The compound...
5.
Britt P, Heiserman J, Snider R, Shill H, Bird C, Wallace R
AJNR Am J Neuroradiol
. 2000 Feb;
21(1):55-9.
PMID: 10669225
Background And Purpose: Occasionally we have observed anecdotal cases of asymptomatic hyperintensities on diffusion-weighted MR (DW-MR) examinations of the brain of patients who previously underwent routine cerebral angiography. These observations,...
6.
Ng H, May K, Bauman J, Ghannam A, Islam I, Liang M, et al.
J Med Chem
. 1999 Dec;
42(22):4680-94.
PMID: 10579830
Ligands for the CCR1 receptor (MIP-1alpha and RANTES) have been implicated in a number of chronic inflammatory diseases, most notably multiple sclerosis and rheumatoid arthritis. Because these ligands share a...
7.
Hesselgesser J, Ng H, Liang M, Zheng W, May K, Bauman J, et al.
J Biol Chem
. 1998 Jun;
273(25):15687-92.
PMID: 9624164
The CC chemokines macrophage inflammatory protein-1alpha (MIP-1alpha) and RANTES (regulated on activation normal T cell expressed) have been implicated in rheumatoid arthritis and multiple sclerosis. Since their effects are mediated...
8.
Wiggins C, Prager C, Snider R
J Health Adm Educ
. 1997 Apr;
15(2):149-54.
PMID: 10174967
At a time when all of healthcare is undergoing change and evolution, the healthcare education community has so far escaped intense public scrutiny. To remain valid, we must address the...
9.
Raddatz R, Crankshaw C, Snider R, Krause J
J Neurochem
. 1995 Mar;
64(3):1183-91.
PMID: 7532207
The substance P (neurokinin-1) receptor belongs to the family of seven putative transmembrane domain receptors that are coupled via G proteins to phospholipase C activation. Homologous desensitization of substance P-stimulated...
10.
Lowe 3rd J, Drozda S, McLean S, Bryce D, Crawford R, Snider R, et al.
J Med Chem
. 1994 Sep;
37(18):2831-40.
PMID: 7520943
The synthesis and structure-activity relationships of a series of aza-tricyclic analogs of the quinuclidine substance P (SP) antagonist 1 are described. The SP receptor affinity of these compounds was found...