R M Sharpe
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Explore the profile of R M Sharpe including associated specialties, affiliations and a list of published articles.
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209
Citations
2495
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Recent Articles
1.
Astuto M, Benford D, Bodin L, Cattaneo I, Halldorsson T, Schlatter J, et al.
Arch Toxicol
. 2022 Nov;
97(2):313-327.
PMID: 36336711
Male reproduction is one of the primary health endpoints identified in rodent studies for some phthalates, such as DEHP (Bis(2-ethylhexyl) phthalate), DBP (Dibutyl phthalate), and BBP (Benzyl butyl phthalate). The...
2.
Rajpert-De Meyts E, Eliasson R, Comhaire F, Skakkebaek N, Sharpe R, Toppari J
Andrology
. 2022 Oct;
10 Suppl 2:133-138.
PMID: 36217708
No abstract available.
3.
Ribaroff G, Wastnedge E, Drake A, Sharpe R, Chambers T
Obes Rev
. 2017 Apr;
18(6):673-686.
PMID: 28371083
Animal models of maternal high fat diet (HFD) demonstrate perturbed offspring metabolism although the effects differ markedly between models. We assessed studies investigating metabolic parameters in the offspring of HFD...
4.
Bellingham M, Fowler P, MacDonald E, Mandon-Pepin B, Cotinot C, Rhind S, et al.
J Neuroendocrinol
. 2016 Nov;
28(12).
PMID: 27870155
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and...
5.
Chambers T, Morgan M, Heger A, Sharpe R, Drake A
Sci Rep
. 2016 Aug;
6:31857.
PMID: 27550193
Experimental and epidemiological evidence demonstrate that ancestral diet might contribute towards offspring health. This suggests that nutrition may be able to modify genetic or epigenetic information carried by germ cells...
6.
7.
Evans N, Bellingham M, Sharpe R, Cotinot C, Rhind S, Kyle C, et al.
J Anim Sci
. 2014 Jun;
92(8):3185-98.
PMID: 24948646
Biosolids (processed human sewage sludge), which contain low individual concentrations of an array of contaminants including heavy metals and organic pollutants such as polycyclic aromatic hydrocarbons (PAH), polychlorinated biphenyls (PCB),...
8.
Auharek S, Lara N, Avelar G, Sharpe R, Franca L
Int J Androl
. 2012 Mar;
35(5):741-51.
PMID: 22420564
Nitric oxide (NO) plays crucial roles in several physiological and pathological conditions. The iNOS isoform produces high levels of NO independent of intracellular calcium and, in the testis, which is...
9.
Dean A, Smith L, MacPherson S, Sharpe R
Int J Androl
. 2012 Jan;
35(3):330-9.
PMID: 22248293
Masculinization is programmed by androgen exposure during a masculinization programming window (MPW). Deficiency in MPW androgen action results in reduced size of all reproductive organs and anogenital distance (AGD) and...
10.
Mitchell R, Childs A, Anderson R, van den Driesche S, Saunders P, McKinnell C, et al.
J Clin Endocrinol Metab
. 2012 Jan;
97(3):E341-8.
PMID: 22238399
Context: Phthalates are ubiquitous environmental chemicals. Fetal exposure to certain phthalates [e.g. di-n-butyl phthalate (DBP)] causes masculinization disorders in rats, raising concern for similar effects in humans. We investigated whether...