R M Sapolsky
Overview
Explore the profile of R M Sapolsky including associated specialties, affiliations and a list of published articles.
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192
Citations
9430
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Recent Articles
1.
Kirby E, Friedman A, Covarrubias D, Ying C, Sun W, Goosens K, et al.
Mol Psychiatry
. 2011 Jun;
17(5):527-36.
PMID: 21670733
Impaired regulation of emotional memory is a feature of several affective disorders, including depression, anxiety and post-traumatic stress disorder. Such regulation occurs, in part, by interactions between the hippocampus and...
2.
Mitra R, Ferguson D, Sapolsky R
Mol Psychiatry
. 2009 Feb;
14(9):847-55, 827.
PMID: 19204724
The basolateral amygdala is critical for generation of anxiety. In addition, exposure to both stress and glucocorticoids induces anxiety. Demonstrated ability of the amygdala to change in response to stress...
3.
Sung J, Zhao H, Roy M, Sapolsky R, Steinberg G
Neuroscience
. 2007 Oct;
149(4):804-12.
PMID: 17945431
Apoptosis, a predominant cause of neuronal death after stroke, can be executed in a caspase-dependent or apoptosis inducing factor (AIF)-dependent manner. Herpes simplex virus (HSV) vectors expressing caspase inhibitors p35...
4.
Vyas A, Kim S, Sapolsky R
Neuroscience
. 2007 Aug;
148(2):342-8.
PMID: 17683872
Parasite Toxoplasma gondii blocks the innate aversion of rats for cat urine, putatively increasing the likelihood of a cat predating a rat. This is thought to reflect an adaptive behavioral...
5.
Nair S, Karst H, Dumas T, Phillips R, Sapolsky R, Rumpff-van Essen L, et al.
Eur J Neurosci
. 2004 Dec;
20(12):3233-43.
PMID: 15610156
Removal of circulating corticosterone by adrenalectomy (ADX) leads to apoptosis after 3 days in a small population of rat dentate granule neurons, whereas most surrounding cells remain viable. Interestingly, a...
6.
Dumas T, Powers E, Tarapore P, Sapolsky R
Hippocampus
. 2004 Aug;
14(6):701-9.
PMID: 15318329
Calcium is a key signaling ion for induction of synaptic plasticity processes that are believed to influence cognition. Mechanisms regulating activity-induced increases in neuronal calcium and related synaptic modifications are...
7.
Kaufer D, Ogle W, Pincus Z, Clark K, Nicholas A, Dinkel K, et al.
Nat Neurosci
. 2004 Aug;
7(9):947-53.
PMID: 15300253
Glucocorticoids, the adrenal steroids released during stress, compromise the ability of neurons to survive neurological injury. In contrast, estrogen protects neurons against such injuries. We designed three genetic interventions to...
8.
Hoehn B, Yenari M, Sapolsky R, Steinberg G
Stroke
. 2003 Sep;
34(10):2489-94.
PMID: 14500933
Background And Purpose: Ischemic injury and reperfusion increases superoxide (O2-) production and reduces the ability of neurons to scavenge free radicals, leading to the release of cytochrome c and apoptosis....
9.
Wingfield J, Sapolsky R
J Neuroendocrinol
. 2003 Jul;
15(8):711-24.
PMID: 12834431
Environmental and social stresses have deleterious effects on reproductive function in vertebrates. Global climate change, human disturbance and endocrine disruption from pollutants are increasingly likely to pose additional stresses that...
10.
Abbott D, Keverne E, Bercovitch F, Shively C, Mendoza S, Saltzman W, et al.
Horm Behav
. 2003 Mar;
43(1):67-82.
PMID: 12614636
Among primate species there is pronounced variation in the relationship between social status and measures of stress physiology. An informal meta-analysis was designed to investigate the basis of this diversity...