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R M Sandoval

Explore the profile of R M Sandoval including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 283
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Recent Articles
1.
Russo L, Sandoval R, Brown D, Molitoris B, Comper W
Kidney Int . 2007 Sep; 72(10):1195-7. PMID: 17851467
For 40 years indirect measurements of the glomerular sieving coefficient of albumin yielded very low values. The first direct measurement by 2-photon microscopy by Russo et al (Kidney Int (2007)...
2.
Ashworth S, Sandoval R, Tanner G, Molitoris B
Kidney Int . 2007 Jun; 72(4):416-21. PMID: 17538570
The introduction of two-photon microscopy, along with the development of new fluorescent probes and innovative computer software, has advanced the study of intracellular and intercellular processes in the tissues of...
3.
Russo L, Sandoval R, McKee M, Osicka T, Collins A, Brown D, et al.
Kidney Int . 2007 Jan; 71(6):504-13. PMID: 17228368
The origin of albuminuria remains controversial owing to difficulties in quantifying the actual amount of albumin filtered by the kidney. Here we use fluorescently labeled albumin, together with the powerful...
4.
Herget-Rosenthal S, Hosford M, Kribben A, Atkinson S, Sandoval R, Molitoris B
Am J Physiol Cell Physiol . 2001 Nov; 281(6):C1858-70. PMID: 11698244
Disruption of the actin cytoskeleton in proximal tubule cells is a key pathophysiological factor in acute renal failure. To investigate dynamic alterations of the actin cytoskeleton in live proximal tubule...
5.
Ashworth S, Sandoval R, Hosford M, Bamburg J, Molitoris B
Am J Physiol Renal Physiol . 2001 Apr; 280(5):F886-94. PMID: 11292632
Breakdown of proximal tubule cell apical membrane microvilli is an early-occurring hallmark of ischemic acute renal failure. Intracellular mechanisms responsible for these apical membrane changes remain unknown, but it is...
6.
Sandoval R, Dunn K, Molitoris B
Am J Physiol Renal Physiol . 2000 Oct; 279(5):F884-90. PMID: 11053049
To study the intracellular mechanisms of aminoglycoside toxicity, we used a 1:1 fluorescent conjugate of Texas Red and gentamicin (TRG) to quantify early uptake dynamics in renal epithelial (LLC-PK(1)) cells....
7.
Parker G, Sandoval R, Feister H, Bidwell J, Rhodes S
J Biol Chem . 2000 May; 275(31):23891-8. PMID: 10818088
LIM homeodomain transcription factors regulate development in complex organisms. To characterize the molecular signals required for the nuclear localization of these proteins, we examined the Lhx3 factor. Lhx3 is essential...
8.
Schwartz N, Hosford M, Sandoval R, Wagner M, Atkinson S, Bamburg J, et al.
Am J Physiol . 1999 Apr; 276(4):F544-51. PMID: 10198413
Apical membrane of renal proximal tubule cells is extremely sensitive to ischemia, with structural alterations occurring within 5 min. These changes are felt secondary to actin cytoskeletal disruption, yet the...